Findings

What do systematic reviews say?

3,006 questions · 3,171 findings · 607 reviews · Headline outcomes only

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No studies found 411 · 13%GRADE not reported 153 · 4.8%Very low 968 · 30.5%Low 897 · 28.3%Moderate 589 · 18.6%High 153 · 4.8%

Metronidazole vs placebo

Malodour (smell score measured on a scale of 0 to 3 with higher scores indicating a more offensive smell) · treating malignant wounds

1 finding from 1 review

Systemic antibiotics for treating malignant wounds 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 6 participants
Very low

Ocriplasmin injection vs control

Mean change in validated visual function questionnaire score from baseline Score ranges from 0 to 100, higher scores are better visual function · people with symptomatic vitreomacular adhesion

1 finding from 1 review

Ocriplasmin for symptomatic vitreomacular adhesion 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Celecoxib vs NSAIDs

Physical function · patients with rheumatoid arthritis

1 finding from 1 review

Celecoxib for rheumatoid arthritis 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 849 participants
Low

Celecoxib vs placebo

Physical function · patients with rheumatoid arthritis

1 finding from 1 review

Celecoxib for rheumatoid arthritis 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 706 participants
Low

Intervention not reported

Health‐related quality of life SF‐36 scale: total score 0‐100, 8 subscales. Higher values mean better health‐related quality of life. · people at risk for development of T2DM

1 finding from 1 review

Dipeptidyl‐peptidase (DPP)‐4 inhibitors and glucagon‐like peptide (GLP)‐1 analogues for prevention or delay of type 2… 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1791 participants
Very low

Intervention not reported

Staff preparedness ‐ asthma knowledge NAKQ 0 to 31 scale; higher is better. 1 to 8 months · school staff

1 finding from 1 review

Asthma education for school staff 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 640 participants
Low

Intervention not reported

Health‐related quality of life (generic) SF‐36 (Physical Component Summary (PCS) score) Scale from 0‐100 Higher value post intervention is favourable, indicating improvement in health‐related quality of life · people with stable COPD

1 finding from 1 review

Singing for adults with chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 52 participants
Low

Intervention not reported

Health‐related quality of life (generic) SF‐36 (Mental Component Sumary (MCS) score) Scale from 0‐100 Higher value post intervention is favourable, indicating improvement in health‐related quality of life · people with stable COPD

1 finding from 1 review

Singing for adults with chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 52 participants
Low

Intervention not reported

Dyspnoea Basal Dyspnea Index (BDI) (score) Scale from 0‐12 Higher value post intervention is favourable, indicating improvement in dyspnoea · people with stable COPD

1 finding from 1 review

Singing for adults with chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

Electrical stimulation vs No active treatment (control)

Incontinence‐specific quality of life · women with stress urinary incontinence

1 finding from 1 review

Electrical stimulation with non‐implanted devices for stress urinary incontinence in women 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 250 participants
Moderate

PFMT added to electrical stimulation vs pelvic floor muscle training (PFMT)

Incontinence‐specific quality of life · women with stress urinary incontinence

1 finding from 1 review

Electrical stimulation with non‐implanted devices for stress urinary incontinence in women 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 193 participants
Very low

Intervention not reported

Motor development and vigor (MDV) domain of the NAPI tool Normative mean and SD at 36 weeks PMA 63 (14.5) Higher scores are associated with more mature behaviour (Snider 2005) · neonates with pain associated with potentially painful procedures for 7 days

1 finding from 1 review

Sucrose for analgesia in newborn infants undergoing painful procedures 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 93 participants
High

Intervention not reported

Alertness and orientation (AO) domain of the NAPI tool Normative mean and SD at 36 weeks PMA 54 (19.4) Higher scores are associated with more mature behaviour (Snider 2005) · neonates with pain associated with potentially painful procedures for 7 days

1 finding from 1 review

Sucrose for analgesia in newborn infants undergoing painful procedures 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 93 participants
High

Droperidol vs haloperidol

Mental state: mean score by 13 days (Scale for Quantification of Psychotic Symptom Severity, high = poor) · acute psychosis

Droperidol showed no clear difference in mental state: mean score by 13 days (Scale for Quantification of… compared with haloperidol (low certainty).

1 finding from 1 review

Droperidol for psychosis‐induced aggression or agitation 2016 · Cochrane Headline outcomes only
MD 0.11
1 study · 40 participants
Low

Statins vs placebo

Cognitive function · older people with normal cognitiona

Statins showed no clear difference in mini Mental State Examination Score Score out of 30 (higher score… compared with placebo (high certainty).

1 finding from 1 review

Statins for the prevention of dementia 2016 · Cochrane Headline outcomes only
MD 0.06
1 study · 5804 participants
High

Evidence‐based psychological interventions vs any comparator

Evidence‐based psychological interventions versus any comparator (Overall) ‐ self‐rated depression scores (higher score is equivalent to a poorer outcome) · Children or adolescents

1 finding from 1 review

Cognitive behavioural therapy (CBT), third‐wave CBT and interpersonal therapy (IPT) based interventions for preventing… 2016 · Cochrane Headline outcomes only
no estimate extracted
73 studies · 13829 participants
Low

Evidence‐based psychological interventions vs any comparator

Evidence‐based psychological interventions versus any comparator (Targeted ‐ self‐rated depression scores (higher score is equivalent to a poorer outcome)) · Children or adolescents

1 finding from 1 review

Cognitive behavioural therapy (CBT), third‐wave CBT and interpersonal therapy (IPT) based interventions for preventing… 2016 · Cochrane Headline outcomes only
no estimate extracted
42 studies · 4816 participants
Moderate

Evidence‐based psychological interventions vs any comparator

Evidence‐based psychological interventions versus any comparator (Universal programmes) ‐ self‐rated depression scores (higher score is equivalent to a poorer outcome) · Children or adolescents

1 finding from 1 review

Cognitive behavioural therapy (CBT), third‐wave CBT and interpersonal therapy (IPT) based interventions for preventing… 2016 · Cochrane Headline outcomes only
no estimate extracted
31 studies · 9013 participants
Moderate

RISPERIDONE DEPOT vs RISPERIDONE

Mental state · patients with schizophrenia

1 finding from 1 review

Risperidone (depot) for schizophrenia 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 591 participants
Moderate

RISPERIDONE DEPOT vs ARIPIPRAZOLE

Clinical response: mean score/change in mental state: mean PANSS total score (high = poor) · patients with schizophrenia

1 finding from 1 review

Risperidone (depot) for schizophrenia 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 349 participants
Low