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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,554 questions in 140 reviews · Heart

current versions
No studies 272 · 17.5%Ungraded 44 · 2.8%Very low 329 · 21.2%Low 464 · 29.9%Moderate 319 · 20.5%High 126 · 8.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Vegan dietary intervention vs another dietary intervention
HDL cholesterol (mmol/L), change from baseline · people with CVD
Vegan dietary pattern for the primary and secondary prevention of cardiovascular diseases (2021) · Cochrane
no estimate extracted1 study · 63 participantsLow
Vegan dietary intervention vs another dietary intervention
Triglycerides (mmol/L), change from baseline · people with CVD
Vegan dietary pattern for the primary and secondary prevention of cardiovascular diseases (2021) · Cochrane
no estimate extracted1 study · 63 participantsVery low
Vegan dietary intervention vs no intervention or minimal intervention
Total cholesterol (mmol/L), change from baseline · people at high risk of CVD
Vegan dietary pattern for the primary and secondary prevention of cardiovascular diseases (2021) · Cochrane
no estimate extracted4 studies · 449 participantsModerate
Vegan dietary intervention vs another dietary intervention
Systolic blood pressure (mmHg), change from baseline · people with CVD
Vegan dietary pattern for the primary and secondary prevention of cardiovascular diseases (2021) · Cochrane
no estimate extracted1 study · 61 participantsVery low
Vegan dietary intervention vs another dietary intervention
Diastolic blood pressure (mmHg), change from baseline · people with CVD
Vegan dietary pattern for the primary and secondary prevention of cardiovascular diseases (2021) · Cochrane
no estimate extracted1 study · 61 participantsVery low
Vegan dietary intervention vs no intervention or minimal intervention
LDL cholesterol (mmol/L), change from baseline · people at high risk of CVD
Vegan dietary pattern for the primary and secondary prevention of cardiovascular diseases (2021) · Cochrane
no estimate extracted4 studies · 449 participantsModerate
Vegan dietary intervention vs no intervention or minimal intervention
HDL cholesterol (mmol/L), change from baseline · people at high risk of CVD
Vegan dietary pattern for the primary and secondary prevention of cardiovascular diseases (2021) · Cochrane
no estimate extracted4 studies · 449 participantsModerate
Vegan dietary intervention vs no intervention or minimal intervention
Triglycerides (mmol/L), change from baseline · people at high risk of CVD
Vegan dietary pattern for the primary and secondary prevention of cardiovascular diseases (2021) · Cochrane
no estimate extracted4 studies · 449 participantsModerate
Vegan dietary intervention vs no intervention or minimal intervention
Systolic blood pressure (mmHg), change from baseline · people at high risk of CVD
Vegan dietary pattern for the primary and secondary prevention of cardiovascular diseases (2021) · Cochrane
no estimate extracted3 studies · 374 participantsLow
Vegan dietary intervention vs no intervention or minimal intervention
Diastolic blood pressure (mmHg), change from baseline · people at high risk of CVD
Vegan dietary pattern for the primary and secondary prevention of cardiovascular diseases (2021) · Cochrane
no estimate extracted3 studies · 372 participantsLow
Vegan dietary intervention vs another dietary intervention
CVD events ‐ not reported · people at high risk of CVD
Vegan dietary pattern for the primary and secondary prevention of cardiovascular diseases (2021) · Cochrane
no estimate extractedNRNo studies
Vegan dietary intervention vs another dietary intervention
Total cholesterol (mmol/L), change from baseline · people at high risk of CVD
Vegan dietary pattern for the primary and secondary prevention of cardiovascular diseases (2021) · Cochrane
no estimate extracted4 studies · 163 participantsLow
Interrupted vs uninterrupted anticoagulation therapy
Outcomes and · adults with arrhythmias undergoing catheter ablation
Interrupted versus uninterrupted anticoagulation therapy for catheter ablation in adults with arrhythmias (2021) · Cochrane
no estimate extractedNRNo studies
Interrupted vs uninterrupted anticoagulation therapy
Thromboembolic events · adults with arrhythmias undergoing catheter ablation
Interrupted versus uninterrupted anticoagulation therapy for catheter ablation in adults with arrhythmias (2021) · Cochrane
RR 1.76 [0.33, 9.46]6 studies · 3468 participantsVery low
Interrupted vs uninterrupted anticoagulation therapy
Major bleeding · adults with arrhythmias undergoing catheter ablation
Interrupted versus uninterrupted anticoagulation therapy for catheter ablation in adults with arrhythmias (2021) · Cochrane
RR 1.1 [0.59, 2.05]10 studies · 4584 participantsLow
Interrupted vs uninterrupted anticoagulation therapy
Composite endpoint of thromboembolic events (stroke or systemic embolism), major bleeding events, and all‐cause mortality · adults with arrhythmias undergoing catheter ablation
Interrupted versus uninterrupted anticoagulation therapy for catheter ablation in adults with arrhythmias (2021) · Cochrane
RR 0.23 [0.07, 0.81]1 study · 442 participantsLow
Interrupted vs uninterrupted anticoagulation therapy
Minor bleeding · adults with arrhythmias undergoing catheter ablation
Interrupted versus uninterrupted anticoagulation therapy for catheter ablation in adults with arrhythmias (2021) · Cochrane
RR 1.01 [0.46, 2.22]9 studies · 3843 participantsVery low
Interrupted vs uninterrupted anticoagulation therapy
All‐cause mortality · adults with arrhythmias undergoing catheter ablation
Interrupted versus uninterrupted anticoagulation therapy for catheter ablation in adults with arrhythmias (2021) · Cochrane
RR 0.34 [0.01, 8.21]1 study · 442 participantsLow
Interrupted vs uninterrupted anticoagulation therapy
Asymptomatic thromboembolic events · adults with arrhythmias undergoing catheter ablation
Interrupted versus uninterrupted anticoagulation therapy for catheter ablation in adults with arrhythmias (2021) · Cochrane
RR 1.45 [0.85, 2.47]6 studies · 1268 participantsVery low
[Axillary] B‐mode ultrasound guidance vs palpation and landmarks
First‐attempt success rate · adults requiring axillary artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Dorsalis pedis] B‐mode ultrasound guidance vs palpation and landmarks
Overall success rate · adults requiring dorsalis pedis artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1 [0.91, 1.1]1 study · 60 participantsVery low
[Dorsalis pedis] B‐mode ultrasound guidance vs palpation and landmarks
Time needed for a successful procedure · adults requiring dorsalis pedis artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted1 study · 60 participantsVery low
[Dorsalis pedis] B‐mode ultrasound guidance vs palpation and landmarks
Major haematoma · adults requiring dorsalis pedis artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Dorsalis pedis] B‐mode ultrasound guidance vs palpation and landmarks
Adverse events (pain) · adults requiring dorsalis pedis artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Dorsalis pedis] B‐mode ultrasound guidance vs palpation and landmarks
Quality of life · adults requiring dorsalis pedis artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound guidance vs palpation and landmarks
First‐attempt success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.44 [1.29, 1.61]27 studies · 4708 participantsLow
[Radial] B‐mode ultrasound guidance vs palpation and landmarks
Pseudomaneurysm · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 2.89 [0.12, 70.63]1 study · 679 participantsVery low
[Radial] B‐mode ultrasound guidance vs palpation and landmarks
Overall success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.11 [1.06, 1.16]28 studies · 4955 participantsLow
[Radial] B‐mode ultrasound guidance vs palpation and landmarks
Time needed for a successful procedure · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted26 studies · 4902 participantsLow
[Radial] B‐mode ultrasound guidance vs palpation and landmarks
Major haematoma · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 0.35 [0.23, 0.56]16 studies · 2504 participantsModerate
[Axillary] B‐mode ultrasound guidance vs palpation and landmarks
Pseudoaneurysm · adults requiring axillary artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound guidance vs palpation and landmarks
Adverse events (pain) · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted4 studies · 883 participantsVery low
[Radial] B‐mode ultrasound guidance vs palpation and landmarks
Quality of life (satisfaction) · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted1 study · 72 participantsVery low
[Radial] B‐mode ultrasound vs Doppler assistance
First‐attempt success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.35 [1.11, 1.64]1 study · 493 participantsModerate
[Radial] B‐mode ultrasound vs Doppler assistance
Pseudoaneurysm · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound vs Doppler assistance
Overall success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.13 [0.99, 1.29]1 study · 493 participantsLow
[Radial] B‐mode ultrasound vs Doppler assistance
Time needed for a successful procedure · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted1 study · 493 participantsModerate
[Radial] B‐mode ultrasound vs Doppler assistance
Major haematoma · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound vs Doppler assistance
Adverse events (pain) · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound vs Doppler assistance
Quality of life · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound vs near‐infrared laser guidance
First‐attempt success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.33 [0.82, 2.16]1 study · 72 participantsVery low
[Axillary] B‐mode ultrasound guidance vs palpation and landmarks
Overall success rate · adults requiring axillary artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.35 [0.99, 1.86]1 study · 33 participantsVery low
[Radial] B‐mode ultrasound vs near‐infrared laser guidance
Pseudoaneurysm · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound vs near‐infrared laser guidance
Overall success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.5 [0.27, 8.45]1 study · 72 participantsVery low
[Radial] B‐mode ultrasound vs near‐infrared laser guidance
Time needed for a successful procedure · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted1 study · 72 participantsVery low
[Radial] B‐mode ultrasound vs near‐infrared laser guidance
Major haematoma · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound vs near‐infrared laser guidance
Adverse events (pain) · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound vs near‐infrared laser guidance
Quality of life · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound vs modified B‐mode ultrasound
First‐attempt success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 0.68 [0.55, 0.84]2 studies · 153 participantsLow
[Radial] B‐mode ultrasound vs modified B‐mode ultrasound
Pseudoaneurysm · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies