Cochrane · systematic review · CD013501
Vegan dietary pattern for the primary and secondary prevention of cardiovascular diseases
Rees, K, Al-Khudairy, L, Takeda, A, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
21
current version
GRADE rated
18
No studies
3
Included studies
NR
No studies 3 · 14.3%Ungraded 0 · 0%Very low 7 · 33.3%Low 4 · 19%Moderate 7 · 33.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Vegan dietary intervention compared to no intervention or minimal intervention for the primary prevention of cardiovascular diseases
Population: people at high risk of CVD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
CVD events ‐ not reported Vegan dietary intervention vs no intervention or minimal intervention | no estimate extracted | NR | No studies |
Total cholesterol (mmol/L), change from baseline Vegan dietary intervention vs no intervention or minimal intervention | no estimate extracted | 4 studies · 449 participants | Moderate Downgraded: imprecision |
LDL cholesterol (mmol/L), change from baseline Vegan dietary intervention vs no intervention or minimal intervention | no estimate extracted | 4 studies · 449 participants | Moderate Downgraded: imprecision |
HDL cholesterol (mmol/L), change from baseline Vegan dietary intervention vs no intervention or minimal intervention | no estimate extracted | 4 studies · 449 participants | Moderate Downgraded: imprecision |
Triglycerides (mmol/L), change from baseline Vegan dietary intervention vs no intervention or minimal intervention | no estimate extracted | 4 studies · 449 participants | Moderate Downgraded: imprecision |
Systolic blood pressure (mmHg), change from baseline Vegan dietary intervention vs no intervention or minimal intervention | no estimate extracted | 3 studies · 374 participants | Low Downgraded: imprecision |
Diastolic blood pressure (mmHg), change from baseline Vegan dietary intervention vs no intervention or minimal intervention | no estimate extracted | 3 studies · 372 participants | Low Downgraded: imprecision |
Vegan dietary intervention compared to another dietary intervention for the primary prevention of cardiovascular diseases
Population: people at high risk of CVD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
CVD events ‐ not reported Vegan dietary intervention vs another dietary intervention | no estimate extracted | NR | No studies |
Total cholesterol (mmol/L), change from baseline Vegan dietary intervention vs another dietary intervention | no estimate extracted | 4 studies · 163 participants | Low Downgraded: imprecision |
LDL cholesterol (mmol/L), change from baseline Vegan dietary intervention vs another dietary intervention | no estimate extracted | 4 studies · 244 participants | Moderate Downgraded: imprecision |
HDL cholesterol (mmol/L), change from baseline Vegan dietary intervention vs another dietary intervention | no estimate extracted | 5 studies · 256 participants | Moderate Downgraded: imprecision |
Triglycerides (mmol/L), change from baseline Vegan dietary intervention vs another dietary intervention | no estimate extracted | 5 studies · 256 participants | Moderate Downgraded: imprecision |
Systolic blood pressure (mmHg), change from baseline Vegan dietary intervention vs another dietary intervention | no estimate extracted | 5 studies · 247 participants | Very low Downgraded: imprecision |
Diastolic blood pressure (mmHg), change from baseline Vegan dietary intervention vs another dietary intervention | no estimate extracted | 5 studies · 247 participants | Very low Downgraded: risk of bias, imprecision |
Vegan dietary intervention compared to another dietary intervention for the secondary prevention of cardiovascular diseases
Population: people with CVD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
CVD events ‐ not reported Vegan dietary intervention vs another dietary intervention | no estimate extracted | NR | No studies |
Total cholesterol (mmol/L), change from baseline Vegan dietary intervention vs another dietary intervention | no estimate extracted | 1 study · 63 participants | Very low Downgraded: risk of bias, imprecision |
LDL cholesterol (mmol/L), change from baseline Vegan dietary intervention vs another dietary intervention | no estimate extracted | 1 study · 62 participants | Very low Downgraded: risk of bias, imprecision |
HDL cholesterol (mmol/L), change from baseline Vegan dietary intervention vs another dietary intervention | no estimate extracted | 1 study · 63 participants | Low Downgraded: risk of bias, imprecision |
Triglycerides (mmol/L), change from baseline Vegan dietary intervention vs another dietary intervention | no estimate extracted | 1 study · 63 participants | Very low Downgraded: risk of bias, imprecision |
Systolic blood pressure (mmHg), change from baseline Vegan dietary intervention vs another dietary intervention | no estimate extracted | 1 study · 61 participants | Very low Downgraded: risk of bias, imprecision |
Diastolic blood pressure (mmHg), change from baseline Vegan dietary intervention vs another dietary intervention | no estimate extracted | 1 study · 61 participants | Very low Downgraded: risk of bias, imprecision |