Tacrolimus vs cyclosporin
- Interventions for idiopathic steroid‐resistant nephrotic syndrome in children 2019 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 58 participantsLow
Tacrolimus may leads to higher number with complete or partial response at one year compared with mycophenolate mofetil to maintain remission (low certainty).
Tacrolimus may leads to higher number with complete response at one year compared with mycophenolate mofetil to maintain remission (low certainty).
Tacrolimus showed no clear difference in number with partial response at one year compared with mycophenolate mofetil to maintain remission (low certainty).
Tacrolimus may leads to lower number with treatment failure by one year compared with mycophenolate mofetil to maintain remission (low certainty).
Tacrolimus may leads to lower number with frequent relapses by one year compared with mycophenolate mofetil to maintain remission (low certainty).
Tacrolimus showed no clear difference in number with steroid resistance by one year compared with mycophenolate mofetil to maintain remission (low certainty).
It is very uncertain whether macrolides changes treatment failure compared with doxycycline (very low certainty).
It is very uncertain whether macrolides changes resolution of fever within 48 hours compared with doxycycline (very low certainty).
Macrolides showed no clear difference in resolution of fever within 5 days compared with doxycycline (low certainty).
Gastrointestinal adverse events in people taking macrolide antibiotics probably leads to higher gastrointestinal disorders not otherwise specified compared with placebo (moderate certainty).
Gastrointestinal adverse events in people taking macrolide antibiotics may leads to higher abdominal pain compared with placebo (low certainty).
Gastrointestinal adverse events in people taking macrolide antibiotics may leads to higher diarrhoea compared with placebo (low certainty).
Gastrointestinal adverse events in people taking macrolide antibiotics probably leads to higher nausea compared with placebo (moderate certainty).
Gastrointestinal adverse events in people taking macrolide antibiotics probably leads to higher vomiting compared with placebo (moderate certainty).
Macroplastique showed no clear difference in number of children with febrile UTI compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (low certainty).
Macroplastique showed no clear difference in number of children with afebrile UTI compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (low certainty).