Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,667 questions · 21,760 findings · 2,177 reviews

No studies found 4,173 · 19.2%GRADE not reported 2,300 · 10.6%Very low 5,276 · 24.2%Low 5,764 · 26.5%Moderate 3,298 · 15.2%High 949 · 4.4%

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Antihistamines vs placebo

Adverse effects: 1. Sedation · patients with motion sickness

Antihistamines may leads to higher adverse effects: sedation Assessed by: adverse effect questionnaire… compared with placebo (low certainty).

1 finding from 1 review

Antihistamines vs placebo

Adverse effects: impaired cognition Assessed by: adverse effect questionnaire (presence or absence given numerical values) · patients with motion sickness

Antihistamines showed no clear difference in adverse effects: impaired cognition Assessed by: adverse effect… compared with placebo (low certainty).

1 finding from 1 review

Antihistamines vs placebo

Adverse effects ‐ Blurred vision No of patients with blurred vision · patients with motion sickness

Antihistamines showed no clear difference in adverse effects: blurred vision Assessed by: adverse effect… compared with placebo (low certainty).

1 finding from 1 review

Whole‐facility changes: Home‐like models vs traditional environment

Depression Revised Memory and Behaviour Problems Checklist (RMBPC) and Mood Scale Score (MSS) (lower scores = better) · older adults living in long‐term residential care including, but not limited to, dementia‐specific care settings
1 finding from 1 review

Intervention not reported

Knowledge and understanding Variable scales: information (amount and type) needs/preferences; discordance between patient and physician survival and curability estimates Timing: immediately to 1 month post‐consultation · people approaching the end of life (within 12 months), their family members and/or carers
1 finding from 1 review

Intervention not reported

Evaluation of the communication: different constructs (perceptions of communication quality; patient‐centredness of communication; involvement preferences; doctor‐patient relationship measures) Timing: immediately post‐consultation to 18 weeks pos... · people approaching the end of life (within 12 months), their family members and/or carers
1 finding from 1 review

Fortification of salt with iron and iodine vs fortification of salt with iodine

Anaemia prevalence · participants were of any age or sex and from any country, regardless of baseline iron and iodine status

Fortification of salt with iron and iodine probably leads to lower prevalence of anaemia compared with fortification of salt with iodine (moderate certainty).

1 finding from 1 review

Fortification of salt with iron and iodine vs fortification of salt with iodine

Prevalence of iron deficiency anaemia · participants were of any age or sex and from any country, regardless of baseline iron and iodine status

Fortification of salt with iron and iodine may leads to lower prevalence of iron deficiency anaemia compared with fortification of salt with iodine (low certainty).

1 finding from 1 review