Cochrane · systematic review · CD013463
Fortification of salt with iron and iodine versus fortification of salt with iodine alone for improving iron and iodine status
Baxter, J-AB, Carducci, B, Kamali, M, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
Developmental, Psychosocial and Learning ProblemsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 71.4%Moderate 1 · 14.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Fortification of salt with iron and iodine versus fortification of salt with iodine for improving iron and iodine status
Population: participants were of any age or sex and from any country, regardless of baseline iron and iodine status
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Haemoglobin concentration (g/dL) Fortification of salt with iron and iodine vs fortification of salt with iodine | no estimate extracted | 13 studies · 4597 participants | Low Downgraded: risk of bias, inconsistency |
Urinary iodine concentration (μg/L) Fortification of salt with iron and iodine vs fortification of salt with iodine | no estimate extracted | 7 studies · 1594 participants | Low Downgraded: imprecision, inconsistency |
Blood pressure (systolic and diastolic) (mmHg) Fortification of salt with iron and iodine vs fortification of salt with iodine | no estimate extracted | NR | No studies |
Ferritin concentration (μg/L) Fortification of salt with iron and iodine vs fortification of salt with iodine | no estimate extracted | 5 studies · 1419 participants | Low Downgraded: imprecision, inconsistency |
Transferrin receptor concentration (mg/L) Fortification of salt with iron and iodine vs fortification of salt with iodine | no estimate extracted | 5 studies · 1256 participants | Low Downgraded: imprecision, inconsistency |
Prevalence of anaemia Fortification of salt with iron and iodine vs fortification of salt with iodine | RR 0.79 [0.66, 0.94] | 8 studies · 2593 participants | Moderate Downgraded: inconsistency |
Prevalence of iron deficiency anaemia Fortification of salt with iron and iodine vs fortification of salt with iodine | RR 0.35 [0.24, 0.52] | 5 studies · 1209 participants | Low Downgraded: imprecision, inconsistency |