Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,536 questions · 2,637 findings · 315 reviews

No studies found 608 · 23.1%GRADE not reported 488 · 18.5%Very low 688 · 26.1%Low 540 · 20.5%Moderate 249 · 9.4%High 64 · 2.4%

Timer watch plus standard urotherapy vs urotherapy alone

Resource implications (e.g. cost of incontinence management methods) · children aged 5 to 14 years with overactive bladder and at least one episode of daytime urinary incontinence per week

The review found no eligible studies for this question.

1 finding from 1 review

Palliative care vs usual care

Adverse effects: at least one serious adverse event · adults with multiple sclerosis Interventions: immunosuppressive and immunomodulatory drugs Comparator: placebo Outcome: withdrawals due to…

Palliative care showed no clear difference in serious adverse events Assessed by: number of participants… compared with usual care (low certainty).

1 finding from 1 review

Intervention not reported

Acetazolamide + medroxyprogesterone versus medroxyprogesterone: risk of AMS · participants at risk of high altitude illness

The intervention showed no clear difference in acetazolamide + medroxyprogesterone versus medroxyprogesterone: risk… (low certainty).

1 finding from 1 review

Intervention not reported

Patient telephone reminder or recall · children, adolescents, and adults with a need for routine immunizations, excluding travel immunizations

The intervention probably leads to higher patient telephone reminder or recall (moderate certainty).

1 finding from 1 review

Intervention not reported

Combination of patient mail and telephone reminder or recall · children, adolescents, and adults with a need for routine immunizations, excluding travel immunizations

The intervention probably leads to higher combination of patient mail and telephone reminder or recall (moderate certainty).

1 finding from 1 review

Lifestyle vs control ‐ Neonatal and later outcomes

Composite outcome in infant (death, shoulder dystocia, nerve palsy, bone fracture) · women with gestational diabetes mellitus

It is very uncertain whether lifestyle changes composite outcome in infant (death, shoulder dystocia, nerve palsy,… compared with control ‐ Neonatal and later outcomes (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse outcome: unintended adverse events attributable to the intervention Multimodal/complex intervention, ATCS Plus, IVR versus various controls · participants at risk of developing long‐term conditions

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Behavioural outcome: breast cancer screening Multimodal/complex intervention versus usual care at 12 months · participants at risk for breast, colorectal or cervical cancer; or osteoporosis

The intervention leads to higher behavioural outcome: breast cancer screening Multimodal/complex… (high certainty).

1 finding from 1 review