Intervention not reported
Maternal puerperal sepsis · pregnant women with PROM
The intervention probably leads to lower maternal puerperal sepsis (moderate certainty).
1 finding from 1 review
RR 0.2
60 participants
Moderate
Probable early‐onset neonatal sepsis ‐ Early induction of labour · pregnant women with prelabour rupture of membranes at or near term
Any antibiotic showed no clear difference in probable early‐onset neonatal sepsis ‐ Early induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (low certainty).
1 finding from 1 review
Serious maternal outcome · pregnant women with prelabour rupture of membranes at or near term
1 finding from 1 review
Probable early‐onset neonatal sepsis ‐ Late induction of labour · pregnant women with prelabour rupture of membranes at or near term
It is very uncertain whether any antibiotic changes probable early‐onset neonatal sepsis ‐ Late induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (very low certainty).
1 finding from 1 review
Definite early‐onset neonatal sepsis ‐ Early induction of labour · pregnant women with prelabour rupture of membranes at or near term
Any antibiotic showed no clear difference in definite early‐onset neonatal sepsis ‐ Early induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (low certainty).
1 finding from 1 review
Definite early‐onset neonatal sepsis ‐ Late induction of labour · pregnant women with prelabour rupture of membranes at or near term
It is very uncertain whether any antibiotic changes definite early‐onset neonatal sepsis ‐ Late induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (very low certainty).
1 finding from 1 review
Maternal infectious morbidity (chorioamnionitis and/or endometritis) ‐ Early induction of labour · pregnant women with prelabour rupture of membranes at or near term
Any antibiotic showed no clear difference in maternal infectious morbidity (chorioamnionitis and/or endometritis)… compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (low certainty).
1 finding from 1 review
Maternal infectious morbidity (chorioamnionitis and/or endometritis) ‐ Late induction of labour · pregnant women with prelabour rupture of membranes at or near term
It is very uncertain whether any antibiotic changes maternal infectious morbidity (chorioamnionitis and/or endometritis)… compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (very low certainty).
1 finding from 1 review
Stillbirth · pregnant women with prelabour rupture of membranes at or near term
Any antibiotic showed no clear difference in stillbirth compared with placebo or no antibiotic (low certainty).
1 finding from 1 review
Perinatal mortality · pregnant women with prelabour rupture of membranes at or near term
Any antibiotic showed no clear difference in perinatal mortality compared with placebo or no antibiotic (low certainty).
1 finding from 1 review
Neonatal mortality · pregnant women with prelabour rupture of membranes at or near term
1 finding from 1 review
Early onset GBS disease (sepsis and/or meningitis within the first seven days of life)) · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants
It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes early onset GBS disease (sepsis and/or meningitis within the first… compared with placebo or no treatment (very low certainty).
1 finding from 1 review
GBS pneumonia within the first seven days of life · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants
It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes GBS pneumonia within the first seven days of life compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Neonatal colonization with GBS within the first seven days of life · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants
It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes neonatal colonization with GBS within the first seven days of life compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Neonatal mortality due to early‐onset GBS infection · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants
1 finding from 1 review
Adverse (mild) effects in the mother · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants
It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes adverse (mild) effects in the mother compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Adverse (mild) effects in the neonate · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants
1 finding from 1 review
Chorioamnionitis Clinical findings · Pregnant women with a gestational age greater than 28 weeks, considered to be in labour receiving chlorhexidine vaginal douching during…
Chlorhexidine vaginal wash showed no clear difference in chorioamnionitis Clinical findings compared with placebo (moderate certainty).
1 finding from 1 review
Postpartum endometritis Clinical findings · Pregnant women with a gestational age greater than 28 weeks, considered to be in labour receiving chlorhexidine vaginal douching during…
Chlorhexidine vaginal wash showed no clear difference in postpartum endometritis Clinical findings compared with placebo (moderate certainty).
1 finding from 1 review
Neonatal sepsis · Pregnant women with a gestational age greater than 28 weeks, considered to be in labour receiving chlorhexidine vaginal douching during…
Chlorhexidine vaginal wash showed no clear difference in neonatal sepsis Clinical findings compared with placebo (low certainty).
1 finding from 1 review