Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,520 questions · 1,575 findings · 175 reviews · Headline outcomes only

No studies found 239 · 15.2%GRADE not reported 59 · 3.7%Very low 337 · 21.4%Low 406 · 25.8%Moderate 410 · 26%High 124 · 7.9%

Intervention not reported

Mortality, due to pneumonia · patients with chronic obstructive pulmonary disease

It is very uncertain whether the intervention changes mortality, due to pneumonia (very low certainty).

1 finding from 1 review

Intervention not reported

Non‐fatal, serious adverse events (all) · patients with chronic obstructive pulmonary disease

The intervention showed no clear difference in non‐fatal, serious adverse events (all) (moderate certainty).

1 finding from 1 review

Intervention not reported

Non‐fatal, serious adverse pneumonia events (requiring hospital admission) · patients with chronic obstructive pulmonary disease

The intervention leads to higher non‐fatal, serious adverse pneumonia events (requiring hospital… (high certainty).

1 finding from 1 review

Intervention not reported

Mortality, due to pneumonia · patients with chronic obstructive pulmonary disease

The intervention showed no clear difference in mortality, due to pneumonia (moderate certainty).

1 finding from 1 review

Intervention not reported

Non‐fatal, serious adverse events (all) · patients with chronic obstructive pulmonary disease

The intervention showed no clear difference in non‐fatal, serious adverse events (all) (high certainty).

1 finding from 1 review

Intervention not reported

Non‐fatal, serious adverse pneumonia events (requiring hospital admission) · patients with chronic obstructive pulmonary disease

The intervention showed no clear difference in non‐fatal, serious adverse pneumonia events (requiring hospital… (moderate certainty).

1 finding from 1 review

Intervention not reported

SGRQ Scores range from 0 to 100, with higher scores indicating more limitations · 18 to 80 years of age with bronchiectasis

The intervention showed no clear difference in SGRQ Scores range from 0 to 100, with higher scores indicating more… (low certainty).

1 finding from 1 review