Findings

What do systematic reviews say?

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

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No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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Psychological therapies vs controls

Migraine‐related disabilitye Lower numbers = lower reported migraine‐related disability · adults with migraine

1 finding from 1 review

Psychological therapies for the prevention of migraine in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 952 participants
Very low

Sit‐stand desk vs no intervention

BellyBra versus Tubigrip ‐ Low‐back Pain · sedentary workers with musculoskeletal symptoms

1 finding from 1 review

Workplace interventions for increasing standing or walking for decreasing musculoskeletal symptoms in sedentary workers 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 79 participants
Low

Multi‐component intervention vs no intervention

Proportion of participants with low back pain/discomfort · sedentary workers with musculoskeletal symptoms

Multi‐component intervention showed no clear difference in proportion of participants with low back pain/discomfort compared with no intervention (low certainty).

1 finding from 1 review

Workplace interventions for increasing standing or walking for decreasing musculoskeletal symptoms in sedentary workers 2019 · Cochrane Headline outcomes only
RR 0.93 [0.69, 1.27]
3 studies · 107 participants
Low

Treadmill workstation vs no intervention

Proportion of participants with low back pain/discomfort · sedentary workers with musculoskeletal symptoms

Treadmill workstation showed no clear difference in proportion of participants with low back pain/discomfort compared with no intervention (low certainty).

1 finding from 1 review

Workplace interventions for increasing standing or walking for decreasing musculoskeletal symptoms in sedentary workers 2019 · Cochrane Headline outcomes only
RR 1.05 [0.5, 2.19]
1 study · 11 participants
Low

Activity tracker vs alternate intervention or no intervention

Proportion of participants with low back pain/discomfort · sedentary workers with musculoskeletal symptoms

1 finding from 1 review

Workplace interventions for increasing standing or walking for decreasing musculoskeletal symptoms in sedentary workers 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 31 participants
Low

Biofeedback plus standard therapy vs sham biofeedback plus standard therapy

Abdominal pain · people with irritable bowel syndrome

1 finding from 1 review

Biofeedback for treatment of irritable bowel syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low

Biofeedback vs counseling

Abdominal pain · people with irritable bowel syndrome

1 finding from 1 review

Biofeedback for treatment of irritable bowel syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 29 participants
Low

Group 1 Pulmonary arterial hypertension ‐ PDE5i vs placebo

QoL · pulmonary arterial hypertension

1 finding from 1 review

Phosphodiesterase 5 inhibitors for pulmonary hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 163 participants
GRADE not reported

Yoga vs an active intervention

Bothersomeness of symptoms at short term (6 weeks) Measured by the Overactive Bladder Symptom and Quality of Life‐Short Form (OABq‐SF) (lower = better) · women with urge‐predominant urinary incontinence

1 finding from 1 review

Yoga for treating urinary incontinence in women 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Yoga vs no specific active intervention

Quality of life (IIQ scores) · women with either stress‐predominant or urge‐predominant urinary incontinence

1 finding from 1 review

Yoga for treating urinary incontinence in women 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low

Yoga vs no specific active intervention

Bothersomeness of symptoms at short term (6 weeks) Measured by Urogenital Distress Inventory 6 (UDI‐6) (lower = better) · women with either stress‐predominant or urge‐predominant urinary incontinence

1 finding from 1 review

Yoga for treating urinary incontinence in women 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low

Systemic corticosteroids vs placebo

Breathlessness (dyspnoea) at 1 week (intensity) Scale 0–10; lower score = less breathlessness · adults with cancer‐related breathlessness (dyspnoea)

1 finding from 1 review

Systemic corticosteroids for the management of cancer‐related breathlessness (dyspnoea) in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 114 participants
Very low

Laparoscopic vs open surgery

Low birthweight · females with inflammatory bowel disease

The review found no eligible studies for this question.

1 finding from 1 review

The impact of surgical therapies for inflammatory bowel disease on female fertility 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Any previous surgery vs no previous surgery

Low birthweight · females with inflammatory bowel disease

It is very uncertain whether any previous surgery changes low birth weight compared with no previous surgery (very low certainty).

1 finding from 1 review

The impact of surgical therapies for inflammatory bowel disease on female fertility 2019 · Cochrane Headline outcomes only
RR 0.61 [0.08, 4.83]
Studies not reported
Very low

IStent in combination with phacoemulsification vs phacoemulsification alone

Mean change in number of IOP‐lowering drops from baseline · open‐angle glaucoma

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 282 participants
Very low

IStent (or iStent inject) vs medical therapy

Mean change in number of IOP‐lowering drops from baseline · open‐angle glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Selexipag vs placebo

Cardiac index · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Moderate

Selexipag vs placebo

RAP · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Moderate

Selexipag vs placebo

Dyspnea · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Moderate

Prostacyclin vs control

Cardiac index · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 868 participants
Low