Cochrane · systematic review · CD012711
The impact of surgical therapies for inflammatory bowel disease on female fertility
Lee, S, Crowe, M, Seow, CH, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
18
current version
GRADE rated
10
No studies
8
Included studies
NR
No studies 8 · 44.4%Ungraded 0 · 0%Very low 10 · 55.6%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Any previous surgery compared to no previous surgery for inflammatory bowel disease on female infertility
Population: females with inflammatory bowel disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Infertilty at 12 months Any previous surgery vs no previous surgery | RR 5.45 [0.41, 72.57] | NR | Very low Downgraded: risk of bias |
Infertility at 24 months Any previous surgery vs no previous surgery | RR 3.59 [1.32, 9.73] | NR | Very low Downgraded: risk of bias |
Miscarriage Any previous surgery vs no previous surgery | OR 2.03 [1.14, 3.6] | NR | Very low Downgraded: risk of bias |
Stillbirth Any previous surgery vs no previous surgery | RR 1.96 [0.42, 9.18] | NR | Very low Downgraded: risk of bias |
Use of ART Any previous surgery vs no previous surgery | RR 25.09 [1.56, 403.76] | NR | Very low Downgraded: risk of bias |
Caesarean section Any previous surgery vs no previous surgery | RR 2.23 [1, 4.95] | NR | Very low Downgraded: risk of bias |
Preterm delivery Any previous surgery vs no previous surgery | RR 1.91 [0.67, 5.48] | NR | Very low Downgraded: risk of bias |
Low birth weight Any previous surgery vs no previous surgery | RR 0.61 [0.08, 4.83] | NR | Very low Downgraded: risk of bias |
Small for gestational age Any previous surgery vs no previous surgery | RR 2.54 [0.8, 8.01] | NR | Very low Downgraded: risk of bias |
Laparoscopic compared to open surgery for inflammatory bowel disease and female infertility
Population: females with inflammatory bowel disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Infertilty at 12 months Laparoscopic vs open surgery | RR 0.7 [0.38, 1.27] | 1 study · 19 participants | Very low Downgraded: risk of bias |
Infertility at 24 months Laparoscopic vs open surgery | no estimate extracted | NR | No studies |
Miscarriage Laparoscopic vs open surgery | no estimate extracted | NR | No studies |
Stillbirth Laparoscopic vs open surgery | no estimate extracted | NR | No studies |
Use of ART Laparoscopic vs open surgery | no estimate extracted | NR | No studies |
Caesarean section Laparoscopic vs open surgery | no estimate extracted | NR | No studies |
Preterm delivery Laparoscopic vs open surgery | no estimate extracted | NR | No studies |
Low birth weight Laparoscopic vs open surgery | no estimate extracted | NR | No studies |
Small for gestational age Laparoscopic vs open surgery | no estimate extracted | NR | No studies |