Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,539 questions · 2,602 findings · 424 reviews · Headline outcomes only

No studies found 572 · 22%GRADE not reported 189 · 7.3%Very low 527 · 20.3%Low 685 · 26.3%Moderate 514 · 19.8%High 115 · 4.4%

Antibiotics vs placebo

Children not cured or substantially improved at · prolonged wet cough in children

Antibiotics probably leads to lower children not cured or substantially improved at compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotics vs placebo

Children with progression of the disease resulting in additional medical therapy (complications) (measured as proportion of participants) · prolonged wet cough in children

Antibiotics probably leads to lower children with progression of the disease resulting in additional… compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotics vs placebo

Adverse effects of antibiotics · prolonged wet cough in children

Antibiotics showed no clear difference in children experiencing adverse effects of antibiotics (e.g.… compared with placebo (low certainty).

1 finding from 1 review

Transfusion of RBCs of shorter vs longer storage duration

Mortality: in‐hospital mortality (within 7 days) · all conditions

It is very uncertain whether transfusion of RBCs of shorter changes mortality: in‐hospital mortality (within 7 days) compared with longer storage duration (very low certainty).

1 finding from 1 review

Summary of findings: feedback on medication adherence to physicians vs usual care

Patient outcomes Lipid levels, HbA1C level, HIV viral load, number of major atherosclerosis disease events · any physician, and any patient treated for chronic diseases with long‐term medication use
1 finding from 1 review

Summary of findings: feedback on medication adherence to physicians vs usual care

Health resource use Rate of hospitalisations, rate of emergency department encounters, rate of outpatient encounters, rate of oral steroid use · any physician, and any patient treated for chronic diseases with long‐term medication use
1 finding from 1 review

Summary of findings: feedback on medication adherence to physicians vs usual care

Processes of care Rate of medication change (medication discontinued, added, replaced), proportion of visits with appropriate management of uncontrolled hypertension, patient rating (quality of care, duration of the visit, communication with physi... · any physician, and any patient treated for chronic diseases with long‐term medication use
1 finding from 1 review