Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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Intervention not reported

Autism symptom severity Measured by: parent‐reported autism symptoms on standardised autism screening and diagnostic instruments (lower scores indicate less severe autism symptoms) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review

Physical and cognitive therapy vs usual care

Cognitive functioning b) Executve functioning (DEX score) (scores range from 0 to 80. Lower scores indicate better functioning) (DEX) · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
1 finding from 1 review

Provision of maize flour or maize flour products fortified with iron plus other vitamins and minerals vs unfortified maize flours or maize flour products

Anaemia · general population older than 2 years of age (including pregnant women), in Kenya and Mexico

It is very uncertain whether provision of maize flour or maize flour products fortified with iron… changes anaemia (defined as haemoglobin (Hb) below WHO cut‐off, adjusted for… compared with unfortified maize flours or maize flour products (very low certainty).

1 finding from 1 review

Serotonin and noradrenaline reuptake inhibitors (SNRI) vs placebo

Self‐reported health‐related quality of life (0‐100 scale) Higher scores indicate higher burden of disease (lower quality of life) · patients with fibromyalgia

Serotonin noradrenaline reuptake inhibitors showed no clear difference in self‐reported health‐related quality of life (0‐100 scale) Higher… compared with placebo (low certainty).

1 finding from 1 review

FIBRINOGEN: Therapeutic trials: intervention vs inactive control

All‐cause mortality Up to 28 days following admission · the prevention and treatment of bleeding in patients without haemophilia

FIBRINOGEN: Therapeutic trials: intervention showed no clear difference in all‐cause mortality Up to 28 days following admission compared with inactive Control (moderate certainty).

1 finding from 1 review