Findings

What do systematic reviews say?

3,454 questions · 3,562 findings · 816 reviews · Headline outcomes only

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No studies found 538 · 15.1%GRADE not reported 239 · 6.7%Very low 933 · 26.2%Low 1,041 · 29.2%Moderate 612 · 17.2%High 199 · 5.6%

Stem cell therapy vs control

Procedural complications · DCM (non‐ischaemic)

1 finding from 1 review

Stem cell therapy for dilated cardiomyopathy 2021 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 361 participants
Very low

Oral iron sulphate vs oral iron hydroxide polymaltose complex

Number of responders · IBD patients

1 finding from 1 review

Interventions for treating iron deficiency anaemia in inflammatory bowel disease 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 41 participants
Very low

Oral iron sulphate vs oral iron hydroxide polymaltose complex

Serious adverse events ‐ active or inactive disease (14 days) · IBD patients

It is very uncertain whether oral iron sulphate changes serious adverse events ‐ active or inactive disease (14 days) compared with oral iron hydroxide polymaltose complex (very low certainty).

1 finding from 1 review

Interventions for treating iron deficiency anaemia in inflammatory bowel disease 2021 · Cochrane Headline outcomes only
RR 2.86 [0.32, 25.24]
1 study · 41 participants
Very low

Low FODMAP diet vs sham diet

Pain frequency IBD (measured in days of pain on the IBS‐SSS questionnaire) · people with inflammatory bowel disease

1 finding from 1 review

Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 52 participants
Very low

Low FODMAP diet vs sham diet

Pain frequency or change in pain frequency · people with inflammatory bowel disease

1 finding from 1 review

Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 52 participants
Very low

Low FODMAP diet vs sham diet

Pain frequency CD (measured in days of pain on the IBS‐SSS questionnaire) · people with inflammatory bowel disease

1 finding from 1 review

Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 26 participants
Very low

A functional programme vs a stretching programme

Physical activity · people with NMD

1 finding from 1 review

Interventions for promoting physical activity in people with neuromuscular disease 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Low

Hydroxychloroquine (HCQ) vs placebo or usual care

Negative PCR for SARS‐CoV‐2 on respiratory samples at day 14 from enrolmentd · adults with mild to severe COVID‐19

Hydroxychloroquine (HCQ) showed no clear difference in negative PCR for SARS‐CoV‐2 on respiratory samples at day 14 from… compared with standard care or placebo (low certainty).

1 finding from 1 review

Chloroquine or hydroxychloroquine for prevention and treatment of COVID‐19 2021 · Cochrane Headline outcomes only
RR 1 [0.91, 1.1]
3 studies · 213 participants
Low

Hydroxychloroquine (HCQ) vs placebo

Development of confirmed COVID‐19 at 14 days from enrolment · people who have been exposed to SARS‐CoV‐2

It is very uncertain whether hydroxychloroquine (HCQ) changes development of confirmed COVID‐19 at 14 days from enrolment compared with placebo (very low certainty).

1 finding from 1 review

Chloroquine or hydroxychloroquine for prevention and treatment of COVID‐19 2021 · Cochrane Headline outcomes only
RR 1.2 [0.5, 2.87]
1 study · 821 participants
Very low

Low FODMAP diet vs sham diet

Pain frequency or change in pain frequency · UC patients

1 finding from 1 review

Interventions for the management of abdominal pain in ulcerative colitis 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 26 participants
Very low

Alternating pressure (active) air surfaces vs foam surfaces

QoL · pressure ulcer prevention

2 findings from 1 review

Alternating pressure (active) air surfaces for preventing pressure ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 267 participants
Low
Alternating pressure (active) air surfaces for preventing pressure ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 233 participants
Low

Foam surfaces vs alternating pressure (active) air surfaces

QoL · pressure ulcer prevention

2 findings from 1 review

Foam surfaces for preventing pressure ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 267 participants
Low
Foam surfaces for preventing pressure ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 233 participants
Low

Exercise vs no exercise

30‐Day mortality · adults with clinically diagnosed AAA deemed suitable for elective repair

It is very uncertain whether exercise changes 30‐day mortality compared with no exercise (very low certainty).

1 finding from 1 review

Prehabilitation exercise therapy before elective abdominal aortic aneurysm repair 2021 · Cochrane Headline outcomes only
RR 1.33 [0.31, 5.77]
3 studies · 192 participants
Very low

Exercise vs no exercise

Duration of ICU stay · adults with clinically diagnosed AAA deemed suitable for elective repair

1 finding from 1 review

Prehabilitation exercise therapy before elective abdominal aortic aneurysm repair 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 147 participants
Very low

Exercise vs no exercise

Length of hospital stay · adults with clinically diagnosed AAA deemed suitable for elective repair

1 finding from 1 review

Prehabilitation exercise therapy before elective abdominal aortic aneurysm repair 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 212 participants
Very low

Exercise vs no exercise

Days on ventilator · adults with clinically diagnosed AAA deemed suitable for elective repair

The review found no eligible studies for this question.

1 finding from 1 review

Prehabilitation exercise therapy before elective abdominal aortic aneurysm repair 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Days at risk of transmitting the infection into the community

1 finding from 1 review

International travel‐related control measures to contain the COVID‐19 pandemic: a rapid review 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intervention not reported

Days at risk of transmitting the infection into the community

1 finding from 1 review

International travel‐related control measures to contain the COVID‐19 pandemic: a rapid review 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intervention not reported

Days at risk of transmitting the infection into the community

1 finding from 1 review

International travel‐related control measures to contain the COVID‐19 pandemic: a rapid review 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Morphine vs fentanyl

Duration of mechanical ventilation · neonates with mechanical ventilation

The review found no eligible studies for this question.

1 finding from 1 review

Opioids for newborn infants receiving mechanical ventilation 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found