Dental caries · Children (<18 years) with vs without dental caries
TaqI/BglI(rs739837) allelic model: T vs G was not significantly associated with dental caries (OR 1.00); ungraded.
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
In the Permanent dentition subgroup, TaqI(rs731236) allelic model: T vs C showed no significant association with caries (OR 0.90); ungraded.
8 findings from 1 review
Show 5 more findings
Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… 2024 All outcomesAllelic model (T vs C) · Children under 18 years; case-control and cross-sectional studies (China, Czech Republic, Turkey, Brazil, India) · Asian ethnicity
OR 0.98 [0.65, 1.50]
Studies not reported
GRADE not reported
Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… 2024 All outcomesAllelic model (T vs C) · Children under 18 years; case-control and cross-sectional studies (China, Czech Republic, Turkey, Brazil, India) · Mixed dentition
OR 0.80 [0.55, 1.15]
Studies not reported
GRADE not reported
Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… 2024 All outcomesAllelic model (T vs C) · Children under 18 years; case-control and cross-sectional studies (China, Czech Republic, Turkey, Brazil, India) · Primary dentition
OR 1.45 [0.96, 2.18]
Studies not reported
GRADE not reported
Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… 2024 All outcomesAllelic model (T vs C) · Children under 18 years; case-control and cross-sectional studies (China, Czech Republic, Turkey, Brazil, India) · Real-time quantitative PCR genotyping
OR 1.24 [0.96, 1.60]
Studies not reported
GRADE not reported
Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… 2024 All outcomesAllelic model (T vs C) · Children under 18 years; case-control and cross-sectional studies (China, Czech Republic, Turkey, Brazil, India) · Caucasian ethnicity
OR 1.00 [0.72, 1.39]
Studies not reported
GRADE not reported
Dental caries · Children (<18 years) with vs without dental caries
FokI(rs10735810) C allele was significantly associated with higher caries risk vs T allele (pooled OR 1.33, 95% CI 1.03-1.71); ungraded.
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
CC+CT genotype at FokI(rs10735810) was associated with ~1.87-fold higher caries risk than TT (dominant model, OR 1.87); ungraded.
1 finding from 1 review
Early childhood caries (ECC) · Children aged 6 years or younger (preschool children)
Serum 25(OH)D <50 nmol/l (vs ≥75 nmol/l) was associated with higher odds of ECC (OR 2.00; ungraded).
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
FokI(rs2228570) recessive model: AA vs AG+GG was not significantly associated with dental caries (OR 1.09); ungraded.
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
In the Real-time quantitative PCR genotyping subgroup, TaqI(rs731236) over-dominant model: TT+CC vs TC showed a significant association with caries (OR 1.52); ungraded.
8 findings from 1 review
Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… 2024 All outcomesOver-dominant model (TT+CC vs TC) · Children under 18 years; case-control and cross-sectional studies (China, Czech Republic, Turkey, Brazil, India) · Real-time quantitative PCR genotyping
OR 1.52 [1.10, 2.10]
Studies not reported
GRADE not reported
Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… 2024 All outcomesOver-dominant model (TT+CC vs TC) · Children under 18 years; case-control and cross-sectional studies (China, Czech Republic, Turkey, Brazil, India) · Primary dentition
OR 1.49 [0.97, 2.28]
Studies not reported
GRADE not reported
Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… 2024 All outcomesOver-dominant model (TT+CC vs TC) · Children under 18 years; case-control and cross-sectional studies (China, Czech Republic, Turkey, Brazil, India) · Asian ethnicity
OR 1.38 [1.02, 1.87]
Studies not reported
GRADE not reported
Show 5 more findings
Intervention not reported
Dental caries prevalence in children
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
FokI(rs2228570) dominant model: AA+AG vs GG was not significantly associated with dental caries (OR 1.07); ungraded.
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
ApaI(rs7975232) dominant model: CC+CA vs AA was not significantly associated with dental caries (OR 0.91); ungraded.
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
Cdx-2(rs11568820) was reported by only one study and was not meta-analyzed; its association with caries risk is uncertain (ungraded).
1 finding from 1 review
Intervention not reported
Dental caries in children
The intervention led to higher dental caries in children; GRADE not reported.
1 finding from 1 review
OR 1.20 [1.04, 1.36]
4 studies
GRADE not reported
Dental caries · Children (<18 years) with vs without dental caries
TaqI/BglI(rs739837) dominant model: TT+TG vs GG was not significantly associated with dental caries (OR 1.09); ungraded.
1 finding from 1 review
Early childhood caries (ECC) · Children aged 6 years or younger (preschool children)
Serum 25(OH)D 50–75 nmol/l (vs ≥75 nmol/l) was associated with higher odds of ECC (OR 1.42; ungraded).
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
After removing Zhang 2006, the recessive model at BsmI(rs1544410) remained non-significant (OR 0.86); ungraded.
2 findings from 1 review
Dental caries · Children (<18 years) with vs without dental caries
After removing Zhang 2006, the over-dominant model at BsmI(rs1544410) remained non-significant (OR 0.85); ungraded.
2 findings from 1 review
Dental caries · Children (<18 years) with vs without dental caries
TaqI/BglI(rs739837) over-dominant model: TT+GG vs TG was not significantly associated with dental caries (OR 0.89); ungraded.
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
Recessive model (CC vs CT+TT) at FokI(rs10735810) showed no significant association with caries (OR 1.23, 95% CI 0.97-1.55); ungraded.
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
ApaI(rs7975232) over-dominant model: CC+AA vs CA was not significantly associated with dental caries (OR 0.91); ungraded.
1 finding from 1 review
Early childhood caries (ECC) · Children aged 6 years or younger (preschool children)
Serum 25(OH)D <50 nmol/l (vs 50–75 nmol/l) was associated with higher odds of ECC (OR 1.47; ungraded).
1 finding from 1 review