Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,511 questions · 2,668 findings · 290 reviews

No studies found 743 · 27.8%GRADE not reported 329 · 12.3%Very low 775 · 29%Low 484 · 18.1%Moderate 279 · 10.5%High 58 · 2.2%

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs conservative interventions

Patient dissatisfaction with the cosmetic result at 1 yearh · adults with acute acromioclavicular dislocation of the shouldera

It is very uncertain whether surgical intervention changes patient dissatisfaction with the cosmetic result at 1 yearh compared with conservative intervention (very low certainty).

1 finding from 1 review

Negative pressure wound therapy vs standard dressing

Surgical site infection · adult patients with surgical wounds healing by primary closure

Negative pressure wound therapy probably leads to lower surgical site infection (proportion of participants in each group… compared with standard dressing (moderate certainty).

1 finding from 1 review

Extended vs short duration antibiotics

Surgical site infections: liver transplant recipients Time frame: 30 days · solid organ transplant recipients

It is very uncertain whether extended changes surgical site infections: liver transplant recipients Time frame: 30… compared with short duration antibiotics (very low certainty).

1 finding from 1 review

Extended vs short duration antibiotics

Surgical site infections: kidney transplant recipients Time frame: 30 days · solid organ transplant recipients

It is very uncertain whether extended changes surgical site infections: kidney transplant recipients Time frame:… compared with short duration antibiotics (very low certainty).

1 finding from 1 review

Azathioprine or 6‐mercaptopurine vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

Surgical relapse · people with surgically‐induced remission in Crohn's disease

It is very uncertain whether azathioprine or 6‐mercaptopurine changes surgical relapse compared with 5‐aminosalicylic acid (very low certainty).

1 finding from 1 review

Topical antibiotics vs no topical antibiotic.

Surgical site infection · people presenting for surgery where healing of surgical wound planned to be by primary intention

Topical antibiotics probably leads to lower surgical site infection compared with no topical antibiotic. (moderate certainty).

1 finding from 1 review

Intervention not reported

Surgical site infection within 30 days in trials with low risk of bias (14 days to 30 days) · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery

The intervention showed no clear difference in surgical site infection within 30 days in trials with low risk of… (low certainty).

1 finding from 1 review

Intervention not reported

Surgical site infection within 30 days, irrespective of risk of bias (14 days to 30 days) · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery

The intervention showed no clear difference in surgical site infection within 30 days, irrespective of risk of bias… (low certainty).

1 finding from 1 review

Early dressing removal vs delayed dressing removal

Postoperative superficial infections · people with surgical site infection

It is very uncertain whether early dressing removal changes superficial surgical site infection Superficial surgical site… compared with delayed dressing removal (very low certainty).

1 finding from 1 review

Surgical miniplates with facemask vs Surgical miniplates with Class III elastics

Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Surgical miniplates with facemask showed no clear difference in overjet compared with surgical miniplates with Class III elastics; GRADE not reported.

1 finding from 1 review

Surgical miniplates with facemask vs Surgical miniplates with Class III elastics

ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Surgical miniplates with facemask showed no clear difference in ANB compared with surgical miniplates with Class III elastics; GRADE not reported.

1 finding from 1 review