Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

391 questions · 421 findings · 30 reviews

No studies found 23 · 5.5%GRADE not reported 30 · 7.1%Very low 136 · 32.3%Low 173 · 41.1%Moderate 58 · 13.8%High 1 · 0.2%

Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs control intervention

Drug or alcohol use, or both following treatment completion ‐ Individual‐based intervention · Individuals with post‐traumatic stress disorder and comorbid substance use disorder

The review found no eligible studies for this question.

1 finding from 1 review

CBT vs alternative treatment

Mental distress · People aged 12 years and over with painful TMD lasting 3 months or longer

Cognitive behavioural therapy (CBT) may leads to lower psychological distress at follow-up compared with alternative (active) treatment (e.g. oral splint, medication,… (low certainty).

2 findings from 1 review

CBT vs inactive control (usual care care, attention control, waitlist)

Mental distress · People aged 12 years and over with painful TMD lasting 3 months or longer

Cognitive behavioural therapy (CBT) showed no clear difference in psychological distress at follow-up compared with usual care, waiting list or no treatment (control) (low certainty).

2 findings from 1 review