Dropouts due to treatment · people who smoke
Bupropion leads to higher dropouts due to treatment compared with placebo/no pharmacological treatment (high certainty).
1 finding from 1 review
Intervention not reported
Pharmacological placebos compared with wait‐list or no‐treatment (Variety of continuous outcome) (Post‐treatment) · patients with mental health disorders
1 finding from 1 review
Bradycardia (requiring pharmacological or pacemaker treatment during the period of study drug administration) · adults undergoing cardiac surgery
Alpha‐2 adrenergic agonists probably leads to higher bradycardia (requiring pharmacological or pacemaker treatment during… compared with control (moderate certainty).
1 finding from 1 review
Bradycardia (requiring pharmacological or pacemaker treatment during the period of study drug administration) · adults undergoing non‐cardiac surgery
1 finding from 1 review
Secondary outcome: acceptability of treatment · depression in adults
1 finding from 1 review
Compliance with treatment · people with schizophrenia with antipsychotic‐induced weight gain
1 finding from 1 review
Compliance with treatment · people with schizophrenia with antipsychotic‐induced weight gain
1 finding from 1 review
Acceptability ‐ total dropouts · women of any age, with PND up to 12 months
It is very uncertain whether antidepressants changes treatment acceptability ‐dropouts compared with any other pharmacological intervention (very low certainty).
1 finding from 1 review
RR 1.74 [0.99, 3.06]
Studies not reported
Very low
Treatment cessation due to adverse events · CRRT
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Any serious adverse event of treatment · people with traumatic head injuries
1 finding from 1 review
Any serious adverse event of treatment count of events · people with traumatic head injuries
Antiepileptic drugs showed no clear difference in any serious adverse event of treatment count of events compared with placebo or standard care (low certainty).
1 finding from 1 review
Any serious adverse event of treatment · people with traumatic head injuries
1 finding from 1 review
Depression symptoms ‐ short‐term · health problem or population
1 finding from 1 review
Depression remission · health problem or population
Summary of findings table ‐ Psychological treatment showed no clear difference in depression remission ‐ short term compared with control (low certainty).
1 finding from 1 review
All‐cause mortality ‐ short‐term · health problem or population
It is very uncertain whether summary of findings table ‐ Psychological treatment changes all‐cause mortality ‐ short‐term compared with control (very low certainty).
1 finding from 1 review
Cardiovascular mortality · health problem or population
Summary of findings table ‐ Psychological treatment showed no clear difference in cardiovascular mortality ‐ long‐term compared with control; GRADE not reported.
1 finding from 1 review
Use of pharmacological pain relief ‐ not reported · pain management in labour
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events as N of participants with at least one adverse event objective · patients with the treatment of cocaine dependence
It is very uncertain whether summary of findings table – disulfiram changes any adverse events (number of participants who experienced at least… compared with placebo or no pharmacological treatment (very low certainty).
1 finding from 1 review
Depression: mean scores at end of treatment (secondary outcome) · people with depression after stroke
1 finding from 1 review
Adverse events: death ‐ at end of treatment (secondary outcome) · people with depression after stroke
1 finding from 1 review