Drowsiness/somnolence (Event rate during treatment, length of treatment varied across trials) · adults with cancer‐related pain
CR oxycodone showed no clear difference in drowsiness/somnolence (Event rate during treatment, length of… compared with CR morphine (low certainty).
1 finding from 1 review
Nausea · adults with cancer‐related pain
CR oxycodone showed no clear difference in nausea (Event rate during treatment, length of treatment varied… compared with CR morphine (low certainty).
1 finding from 1 review
Vomiting · adults with cancer‐related pain
It is very uncertain whether CR oxycodone changes vomiting (Event rate during treatment, length of treatment varied… compared with CR morphine (very low certainty).
1 finding from 1 review
Quality of life · adults with cancer‐related pain
It is very uncertain whether CR oxycodone changes quality of life compared with CR morphine (very low certainty).
1 finding from 1 review
Participant preference · adults with cancer‐related pain
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults with cancer‐related pain
CR oxycodone may leads to higher pain intensity (various pain intensity scales; SMD) compared with CR morphine (low certainty).
1 finding from 1 review
Nausea · people with moderate to severe cancer pain
It is very uncertain whether hydromorphone changes specific adverse events – nausea compared with morphine (very low certainty).
1 finding from 1 review
Vomiting · people with moderate to severe cancer pain
It is very uncertain whether hydromorphone changes specific adverse events – vomiting compared with morphine (very low certainty).
1 finding from 1 review
Dizziness · people with moderate to severe cancer pain
It is very uncertain whether hydromorphone changes specific adverse events – dizziness compared with morphine (very low certainty).
1 finding from 1 review
Constipation · people with moderate to severe cancer pain
1 finding from 1 review
Quality of life · people with moderate to severe cancer pain
The review found no eligible studies for this question.
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people with moderate to severe cancer pain
1 finding from 1 review
Relief of pain · people with moderate to severe cancer pain
It is very uncertain whether hydromorphone changes participant‐reported pain relief compared with morphine (very low certainty).
1 finding from 1 review
Birthweight (g) · opiate‐dependent pregnant women
1 finding from 1 review
APGAR score (APGAR score ) · opiate‐dependent pregnant women
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events for the mother · opiate‐dependent pregnant women
1 finding from 1 review
Serious adverse events for the child · opiate‐dependent pregnant women
1 finding from 1 review
Unacceptability of treatment (dropouts/exclusions during the trial) · opiate‐dependent pregnant women
1 finding from 1 review
Use of substance · opiate‐dependent pregnant women
Methadone showed no clear difference in use of substance compared with oral slow‐release morphine (low certainty).
1 finding from 1 review
Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Low