CR oxycodone vs CR morphine: Drowsiness/somnolence (Event rate during treatment, length of treatment varied across trials)
- Population
- adults with cancer‐related pain
- Intervention
- CR oxycodone
- Comparison
- CR morphine
- Outcome
- Drowsiness/somnolence (Event rate during treatment, length of treatment varied across trials)
CR oxycodone showed no clear difference in drowsiness/somnolence (Event rate during treatment, length of… compared with CR morphine (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
CR oxycodone vs CR morphine Drowsiness/somnolence (Event rate during treatment, length of treatment varied across trials) · adults with cancer‐related pain CR oxycodone showed no clear difference in drowsiness/somnolence (Event rate during treatment, length of… compared with CR morphine (low certainty). Oxycodone for cancer‐related pain (2022) · Cochrane Headline outcomes only | RR 0.88 [0.74, 1.05] | 15 studies · 1486 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Oxycodone for cancer‐related pain 2022 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- CR oxycodone vs IR oxycodone · adults with cancer‐related pain · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.