Findings

What do systematic reviews say?

145 questions · 145 findings · 20 reviews · Hypertension

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No studies found 20 · 13.8%GRADE not reported 4 · 2.8%Very low 19 · 13.1%Low 32 · 22.1%Moderate 23 · 15.9%High 47 · 32.4%

Intervention not reported

LDL‐cholesterol atorvastatin 80 mg/d · individuals with normal or abnormal lipid profiles

1 finding from 1 review

Atorvastatin for lowering lipids 2015 · Cochrane Headline outcomes only
no estimate extracted
37 studies · 4281 participants
High

Intervention not reported

WDAEb all doses · individuals with normal or abnormal lipid profiles

1 finding from 1 review

Atorvastatin for lowering lipids 2015 · Cochrane Headline outcomes only
no estimate extracted
34 studies · 3688 participants
Very low

Intervention not reported

Systolic blood pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of monotherapy with thiazide diuretics for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 663 participants
Moderate

Intervention not reported

Diastolic blood pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of monotherapy with thiazide diuretics for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 662 participants
Moderate

Intervention not reported

Systolic blood pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of monotherapy with thiazide diuretics for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
47 studies · 7733 participants
High

Intervention not reported

Diastolic blood pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of monotherapy with thiazide diuretics for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
51 studies · 8064 participants
High

Intervention not reported

Withdrawal due to adverse effects · adults with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of monotherapy with thiazide diuretics for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
20 studies · 3698 participants
Very low

Intervention not reported

Decrease in systolic blood pressure · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 490 participants
Very low

Intervention not reported

Decrease in diastolic blood pressure · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 490 participants
Very low

Intervention not reported

Decrease in heart rate · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 256 participants
Very low

Intervention not reported

Decrease in pulse pressure · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 490 participants
Very low

Intervention not reported

Withdrawal due to adverse effect · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 117 participants
Very low

Nonselective beta‐blockers vs placebo

SBP (mmHg) · adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of nonselective beta‐blockers for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 948 participants
Low

Nonselective beta‐blockers vs placebo

Diastolic blood pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of nonselective beta‐blockers for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 948 participants
Low

Nonselective beta‐blockers vs placebo

Heart rate · adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of nonselective beta‐blockers for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 864 participants
Low

Nonselective beta‐blockers vs placebo

Pulse pressure · adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of nonselective beta‐blockers for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 948 participants
Very low

Nonselective beta‐blockers vs placebo

Withdrawals due to adverse events · adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of nonselective beta‐blockers for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 729 participants
Low

Dihydropyridine calcium channel blockers vs placebo

Variation in the decrease in 24‐hour ambulatory hourly SBP (at 3 to 12 weeks) · adults with primary hypertension

1 finding from 1 review

Time course for blood pressure lowering of dihydropyridine calcium channel blockers 2014 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 2768 participants
Moderate

Dihydropyridine calcium channel blockers vs placebo

Variation in the decrease in 24‐hour ambulatory hourly DBP (at 3 to 12 weeks) · adults with primary hypertension

1 finding from 1 review

Time course for blood pressure lowering of dihydropyridine calcium channel blockers 2014 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 2768 participants
Moderate

Intervention not reported

LDL‐Cholesterol rosuvastatin 2.5 mg/day · participantswith normal or abnormal lipid profiles

1 finding from 1 review

Rosuvastatin for lowering lipids 2014 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 450 participants
Low