Cochrane · systematic review · CD008226

Atorvastatin for lowering lipids

Adams, SP, Tsang, M, Wright, JM · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Hypertension2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 20%Low 0 · 0%Moderate 0 · 0%High 4 · 80%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

LDL‐cholesterol‐lowering efficacy of atorvastatin

Population: individuals with normal or abnormal lipid profiles
5 questions
OutcomeEffectEvidenceStatus / GRADE
LDL‐cholesterol atorvastatin 10 mg/d
no estimate extracted188 studies · 21941 participantsHigh
LDL‐cholesterol atorvastatin 20 mg/d
no estimate extracted80 studies · 9310 participantsHigh
LDL‐cholesterol atorvastatin 40 mg/d
no estimate extracted37 studies · 3296 participantsHigh
LDL‐cholesterol atorvastatin 80 mg/d
no estimate extracted37 studies · 4281 participantsHigh
WDAEb all doses
no estimate extracted34 studies · 3688 participantsVery low
Downgraded: risk of bias, imprecision