Cochrane · systematic review · CD008226
Atorvastatin for lowering lipids
Adams, SP, Tsang, M, Wright, JM · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 20%Low 0 · 0%Moderate 0 · 0%High 4 · 80%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyLDL‐cholesterol‐lowering efficacy of atorvastatin
Population: individuals with normal or abnormal lipid profiles
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
LDL‐cholesterol atorvastatin 10 mg/d | no estimate extracted | 188 studies · 21941 participants | High |
LDL‐cholesterol atorvastatin 20 mg/d | no estimate extracted | 80 studies · 9310 participants | High |
LDL‐cholesterol atorvastatin 40 mg/d | no estimate extracted | 37 studies · 3296 participants | High |
LDL‐cholesterol atorvastatin 80 mg/d | no estimate extracted | 37 studies · 4281 participants | High |
WDAEb all doses | no estimate extracted | 34 studies · 3688 participants | Very low Downgraded: risk of bias, imprecision |
LDL‐cholesterol lowering efficacy of atorvastatin
Population: subjects with normal or abnormal lipid profiles
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
LDL‐C atorvastatin 10 mg/day | no estimate extracted | 160 studies · 19601 participants | High |
LDL‐C atorvastatin 20 mg/day | no estimate extracted | 69 studies · 7868 participants | High |
LDL‐C atorvastatin 40 mg/day | no estimate extracted | 35 studies · 2836 participants | High |
LDL‐C atorvastatin 80 mg/day | no estimate extracted | 32 studies · 3300 participants | High |