Cochrane · systematic review · CD010052

Time course for blood pressure lowering of dihydropyridine calcium channel blockers

Ghamami, N, Chiang, SHY, Dormuth, C, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

HypertensionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
2
current version
GRADE rated
2
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Dihydropyridine calcium channel blockers compared with placebo for hypertension

Population: adults with primary hypertension
2 questions
OutcomeEffectEvidenceStatus / GRADE
Variation in the decrease in 24‐hour ambulatory hourly systolic blood pressure at 3‐12 weeks
Dihydropyridine calcium channel blockers vs placebo
no estimate extracted16 studies · 2768 participantsModerate
Downgraded: risk of bias, inconsistency
Variation in the decrease in 24‐hour ambulatory hourly diastolic blood pressure at 3‐12 weeks
Dihydropyridine calcium channel blockers vs placebo
no estimate extracted16 studies · 2768 participantsModerate
Downgraded: risk of bias, inconsistency