Cochrane · systematic review · CD007452

Blood pressure lowering efficacy of nonselective beta‐blockers for primary hypertension

Wong, GWK, Wright, JM · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

HypertensionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 20%Low 4 · 80%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Nonselective beta‐blockers compared with placebo for primary hypertension

Population: adults with primary hypertension
5 questions
OutcomeEffectEvidenceStatus / GRADE
SBP (mmHg)
Nonselective beta‐blockers vs placebo
no estimate extracted16 studies · 948 participantsLow
DBP (mmHg)
Nonselective beta‐blockers vs placebo
no estimate extracted16 studies · 948 participantsLow
Heart rate (beats per minute)
Nonselective beta‐blockers vs placebo
no estimate extracted13 studies · 864 participantsLow
Pulse pressure (mmHg)
Nonselective beta‐blockers vs placebo
no estimate extracted16 studies · 948 participantsVery low
Withdrawal due to adverse effect
Nonselective beta‐blockers vs placebo
no estimate extracted2 studies · 729 participantsLow