Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

193 questions · 196 findings · 33 reviews

No studies found 21 · 10.7%GRADE not reported 16 · 8.2%Very low 43 · 21.9%Low 52 · 26.5%Moderate 49 · 25%High 15 · 7.7%

Automated mandatory bolus vs basal infusion

Breakthrough pain · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

Automated mandatory bolus probably leads to lower breakthrough pain compared with basal infusion (moderate certainty).

1 finding from 1 review

Upright position vs recumbent position

Operative birth (caesarean or instrumental vaginal) · women in the second stage of labour with epidural anaesthesia

Upright position leads to higher operative birth (caesarean or instrumental vaginal) compared with recumbent position (sensitivity analyses ‐ studies at low risk of… (high certainty).

2 findings from 1 review

Upright position vs recumbent position

Caesarean section · women in the second stage of labour with epidural anaesthesia

Upright position leads to higher caesarean section compared with recumbent position (sensitivity analyses ‐ studies at low risk of… (high certainty).

2 findings from 1 review

Upright position vs recumbent position

Instrumental vaginal birth · women in the second stage of labour with epidural anaesthesia

Upright position showed no clear difference in instrumental vaginal birth compared with recumbent position (sensitivity analyses ‐ studies at low risk of… (low certainty).

2 findings from 1 review

Upright position vs recumbent position

Blood loss (greater than 500 mL) (trial authors defined it as PPH requiring blood transfusion) · women in the second stage of labour with epidural anaesthesia

Upright position showed no clear difference in blood loss (greater than 500 mL) (trial authors defined it as PPH… compared with recumbent position (moderate certainty).

1 finding from 1 review