Piperacillin vs ampicillin plus amikacin
It is very uncertain whether piperacillin changes nephrotoxicity maximum compared with ampicillin plus amikacin (very low certainty).
- RR 1.14 [0.8, 1.61]1 study · 396 participantsVery low
It is very uncertain whether piperacillin changes nephrotoxicity maximum compared with ampicillin plus amikacin (very low certainty).
It is very uncertain whether ampicillin plus gentamicin changes serious adverse events maximum compared with penicillin plus gentamicin (very low certainty).
It is very uncertain whether ampicillin plus gentamicin changes circulatory support maximum compared with penicillin plus gentamicin (very low certainty).
It is very uncertain whether ampicillin plus gentamicin changes neurological developmental impairment maximum compared with penicillin plus gentamicin (very low certainty).
It is very uncertain whether ampicillin plus gentamicin changes necrotising enterocolitis maximum compared with penicillin plus gentamicin (very low certainty).
It is very uncertain whether piperacillin plus tazobactam changes all‐cause mortality maximum compared with amikacin (very low certainty).
It is very uncertain whether piperacillin plus tazobactam changes serious adverse events maximum compared with amikacin (very low certainty).
It is very uncertain whether ticarcillin plus clavulanic acid changes all‐cause mortality maximum compared with piperacillin plus gentamicin (very low certainty).
It is very uncertain whether ticarcillin plus clavulanic acid changes serious adverse events maximum compared with piperacillin plus gentamicin (very low certainty).
Late parenteral nutrition may leads to lower in‐hospital all‐cause mortality compared with early parenteral nutrition (low certainty).
Late parenteral nutrition may leads to lower neonatal mortality (within 28 days of birth) compared with early parenteral nutrition (low certainty).
Late parenteral nutrition showed no clear difference in healthcare‐associated blood stream infection compared with early parenteral nutrition (low certainty).
Late parenteral nutrition may leads to lower healthcare‐associated infection (any type) compared with early parenteral nutrition (low certainty).
Late parenteral nutrition showed no clear difference in mean duration of hospital stay compared with early parenteral nutrition (low certainty).
Late parenteral nutrition showed no clear difference in mean duration of mechanical ventilation compared with early parenteral nutrition (low certainty).
Late parenteral nutrition showed no clear difference in hypoglycaemia compared with early parenteral nutrition (low certainty).
Regional (spinal, epidural, caudal) showed no clear difference in apnoea/bradycardia occurring 12‐24 hours following completion of… compared with general anaesthesia (moderate certainty).