Cochrane · systematic review · CD013141
Early versus late parenteral nutrition for critically ill term and late preterm infants
Moon, K, Athalye‐Jape, GK, Rao, U, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 7 · 100%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Late parenteral nutrition compared to early parenteral nutrition for critically ill term and late preterm infants
Population: critically ill term and late preterm infants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
In‐hospital all‐cause mortality Late parenteral nutrition vs early parenteral nutrition | RR 0.35 [0.14, 0.87] | 1 study · 209 participants | Low Downgraded: risk of bias |
Neonatal mortality (within 28 days of birth) Late parenteral nutrition vs early parenteral nutrition | RR 0.29 [0.1, 0.88] | 1 study · 209 participants | Low Downgraded: risk of bias |
Healthcare‐associated blood stream infection Late parenteral nutrition vs early parenteral nutrition | RR 0.22 [0.05, 1.01] | 1 study · 209 participants | Low Downgraded: risk of bias |
Healthcare‐associated infection (any type) Late parenteral nutrition vs early parenteral nutrition | RR 0.53 [0.32, 0.89] | 1 study · 209 participants | Low Downgraded: risk of bias |
Mean duration of hospital stay Late parenteral nutrition vs early parenteral nutrition | MD 9.5 | 1 study · 209 participants | Low Downgraded: risk of bias |
Mean duration of mechanical ventilation Late parenteral nutrition vs early parenteral nutrition | MD 3.4 | 1 study · 209 participants | Low Downgraded: risk of bias |
Hypoglycaemia Late parenteral nutrition vs early parenteral nutrition | RR 1.64 [0.91, 2.96] | 1 study · 209 participants | Low Downgraded: risk of bias |