Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between AG + GG genotype (G-allele carriers) vs AA genotype of ENAM rs1264848 and dental caries susceptibility (AG + GG vs AA model: OR 1.69, 95% CI 0.78-3.68) in the Ethnicity: Mixed subgroup; certainty not graded.
6 findings from 1 review
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Dental caries · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
rs1126478 showed no significant association with dental caries under a co-dominant model (OR 0.97, 95% CI 0.72 to 1.32; ungraded).
1 finding from 1 review
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between TT genotype vs CC + CT genotype of AMELX rs946252 and dental caries susceptibility (TT vs CC + CT model: OR 0.73, 95% CI 0.19-2.87) in the Control group: Caries-free subgroup; certainty not graded.
6 findings from 1 review
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Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between T allele vs C allele of AMELX rs6639060 and dental caries susceptibility (T vs C model: OR 1.08, 95% CI 0.63-1.85) in the Ethnicity: Caucasian subgroup; certainty not graded.
3 findings from 1 review
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between TT genotype vs CC genotype of AMELX rs2106416 and dental caries susceptibility (TT vs CC model: OR 1.83, 95% CI 0.47-7.06); certainty not graded.
3 findings from 1 review
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between TT genotype vs CC + CT genotype of ENAM rs3796703 and dental caries susceptibility (TT vs CC + CT model: OR 2.90, 95% CI 0.92-9.12); certainty not graded.
3 findings from 1 review
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between T allele vs C allele of AMELX rs2106416 and dental caries susceptibility (T vs C model: OR 0.59, 95% CI 0.16-2.11); certainty not graded.
3 findings from 1 review
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between CT genotype vs CC genotype of ENAM rs3796703 and dental caries susceptibility (CT vs CC model: OR 0.89, 95% CI 0.23-3.48) in the Ethnicity: Asian subgroup; certainty not graded.
3 findings from 1 review
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between TT genotype vs CC genotype of ENAM rs3796703 and dental caries susceptibility (TT vs CC model: OR 5.22, 95% CI 0.25-108.96) in the Ethnicity: Asian subgroup; certainty not graded.
3 findings from 1 review
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between CT + TT genotype (T-allele carriers) vs CC genotype of ENAM rs3796703 and dental caries susceptibility (CT + TT vs CC model: OR 0.90, 95% CI 0.23-3.63); certainty not graded.
3 findings from 1 review
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between TT genotype vs CC + CT genotype of AMELX rs6639060 and dental caries susceptibility (TT vs CC + CT model: OR 1.00, 95% CI 0.42-2.39) in the Ethnicity: Caucasian subgroup; certainty not graded.
3 findings from 1 review
Dental caries · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
LTF rs11716497 showed no significant association with dental caries in a single study (OR 1.04, 95% CI 0.90 to 1.21; ungraded).
1 finding from 1 review
Dental caries · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
LTF rs11216477 was significantly associated with dental caries in a single study (OR 1.17, 95% CI 1.06 to 1.29; ungraded).
1 finding from 1 review
Dental caries · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
The additive-model association remained non-significant after excluding the adult-data study (OR 1.47, 95% CI 0.92 to 2.35; ungraded).
2 findings from 1 review
Dental caries · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
rs1126478 showed no significant association with dental caries under an allelic model (OR 1.41, 95% CI 0.48 to 4.13; ungraded).
1 finding from 1 review
Dental caries · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
rs1126478 showed no significant association with dental caries under a recessive model (OR 1.55, 95% CI 0.44 to 5.38; ungraded).
1 finding from 1 review
Dental caries · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
rs1126478 showed no significant association with dental caries under a dominant model (OR 1.32, 95% CI 0.43 to 4.03; ungraded).
1 finding from 1 review
Dental caries · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
LTF rs6441989 showed no significant association with dental caries in a single study (OR 1.02, 95% CI 0.92 to 1.14; ungraded).
1 finding from 1 review
Dental caries · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
LTF rs2073495 showed no significant association with dental caries in a single study (OR 0.99, 95% CI 0.86 to 1.15; ungraded).
1 finding from 1 review
CA VI activity · Children (age about 2-9 years) across the 7 meta-analyzed activity samples; excludes Kivela 1999 adults (18-24 years), qualitative only…
Salivary/biofilm CA VI activity is significantly higher in individuals with dental caries than in caries-free individuals (SMD 0.894, 95% CI 0.386 to 1.392; not GRADE-rated).
1 finding from 1 review