Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

197 questions · 212 findings · 20 reviews · Acute Respiratory Infections

No studies found 37 · 17.5%GRADE not reported 19 · 9%Very low 25 · 11.8%Low 35 · 16.5%Moderate 67 · 31.6%High 29 · 13.7%

Probiotics vs placebo

Proportion of children with AOM: children not prone to AOM · children up to age 18 years

Probiotic probably leads to lower proportion of children with AOM: children not prone to AOM compared with placebo (moderate certainty).

1 finding from 1 review

Probiotics vs placebo

Proportion of children with AOM: children prone to AOM · children up to age 18 years

Probiotic showed no clear difference in proportion of children with AOM: children prone to AOM compared with placebo (high certainty).

1 finding from 1 review

Probiotics vs placebo

Difference in proportion of children with other infections · children up to age 18 years

Probiotic probably leads to lower difference in proportion of children with other infections compared with placebo (moderate certainty).

1 finding from 1 review

Live attenuated influenza vaccine vs placebo or no intervention

Influenza assessed by laboratory confirmation · healthy, community‐dwelling children younger than 16 years of age

Live attenuated influenza vaccine probably leads to lower influenza assessed by laboratory confirmation compared with placebo or do nothing (moderate certainty).

1 finding from 1 review