Question · asked by 1 review
Probiotics vs placebo: Adverse events
- Population
- children up to age 18 years
- Intervention
- Probiotics
- Comparison
- placebo
- Outcome
- Adverse events
Probiotic showed no clear difference in adverse events compared with placebo (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Probiotic vs placebo Adverse events · children up to age 18 years Probiotic showed no clear difference in adverse events compared with placebo (low certainty). Probiotics for preventing acute otitis media in children (2019) · Cochrane Headline outcomes only | OR 1.54 [0.6, 3.94] | 4 studies · 395 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Probiotics for preventing acute otitis media in children 2019 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
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How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.