Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

428 questions · 430 findings · 82 reviews

No studies found 89 · 20.7%GRADE not reported 33 · 7.7%Very low 93 · 21.6%Low 110 · 25.6%Moderate 79 · 18.4%High 26 · 6%

Chemotherapy alone vs same chemotherapy plus radiotherapy

Secondary malignant neoplasms · Patients with untreated Hodgkin lymphoma (early and advanced stages)

Chemotherapy alone may leads to lower secondary malignant neoplasms compared with same chemotherapy plus radiotherapy (low certainty).

1 finding from 1 review

Chemotherapy alone vs same chemotherapy plus radiotherapy

Death · Patients with untreated Hodgkin lymphoma (early and advanced stages)

Chemotherapy alone showed no clear difference in death compared with same chemotherapy plus radiotherapy (moderate certainty).

1 finding from 1 review

Chemotherapy alone vs same chemotherapy plus radiotherapy

Progression/relapse · Patients with untreated Hodgkin lymphoma (early and advanced stages)

Chemotherapy alone showed no clear difference in progression/relapse compared with same chemotherapy plus radiotherapy (moderate certainty).

1 finding from 1 review

Continuous chest compression alone vs interrupted chest compression plus artificial ventilation

Survival to hospital discharge · Patients with non‐trauma related out‐of‐hospital cardiac arrest

Continuous chest compression alone leads to higher survival to hospital discharge compared with interrupted chest compression plus artificial ventilation (high certainty).

1 finding from 1 review

Continuous chest compression alone vs interrupted chest compression plus artificial ventilation

Survival to hospital admission · Patients with non‐trauma related out‐of‐hospital cardiac arrest

Continuous chest compression alone showed no clear difference in survival to hospital admission compared with interrupted chest compression plus artificial ventilation (moderate certainty).

1 finding from 1 review

Continuous chest compression alone vs interrupted chest compression plus artificial ventilation

Neurological function at hospital discharge, measured by cerebral performance category (CPC) · Patients with non‐trauma related out‐of‐hospital cardiac arrest

Continuous chest compression alone showed no clear difference in neurological outcomes at hospital discharge Measured as 'good' or… compared with interrupted chest compression plus artificial ventilation (moderate certainty).

1 finding from 1 review

LongoVital (herbal component alone) vs placebo

General degree of discomfort · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

LongoVital (herbal component alone) showed no clear difference in general degree of discomfort compared with placebo; GRADE not reported.

1 finding from 1 review

LongoVital (herbal component alone) vs placebo

Number of days of pain (monthly average) · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

LongoVital (herbal component alone) showed no clear difference in number of days of pain (monthly average) compared with placebo; GRADE not reported.

1 finding from 1 review

LongoVital (herbal component alone) vs placebo

Mean size of ulcers · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

LongoVital (herbal component alone) showed no clear difference in mean size of ulcers compared with placebo; GRADE not reported.

1 finding from 1 review

LongoVital (herbal component alone) vs placebo

Number of days of ulcers (monthly average) · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

LongoVital (herbal component alone) showed no clear difference in number of days of ulcers (monthly average) compared with placebo; GRADE not reported.

1 finding from 1 review

LongoVital (herbal component alone) vs placebo

Number of ulcer-free days and number of new ulcers · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
  • Kolseth 2005 (high risk of bias): 40 patients randomised to the herbal component of LongoVital alone or placebo; data presented as medians with 95% CIs, unsuitable for further analysis; no statistically significant…
    1 study · 40 participants
    GRADE not reported

LongoVital (herbal component alone) vs placebo

Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review