Question · asked by 1 review

LongoVital (herbal component alone) vs placebo: Number of ulcer-free days and number of new ulcers

Population
Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination; excluding those with Behcet's disease, Reiter's syndrome, recurrent erythema multiforme, viral infection, coeliac disease, Crohn's disease, ulcerative colitis, anaemia or haematinic deficiency
Intervention
LongoVital (herbal component alone)
Comparison
placebo
Outcome
Number of ulcer-free days and number of new ulcers

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
LongoVital (herbal component alone) vs Placebo
Number of ulcer-free days and number of new ulcers · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and… · 4 months
Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) (2012) · Cochrane All outcomes
Kolseth 2005 (high risk of bias): 40 patients randomised to the herbal component of LongoVital alone or placebo; data presented as medians with 95% CIs, unsuitable for further analysis; no statistically significant…1 study · 40 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Systemic interventions for recurrent aphthous stomatitis (mouth ulcers)
2012 · Cochrane All outcomes
2012-06Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.