Intervention not reported
0.5% CMC vs. 0.3% HPMC · people with dry eye
1 finding from 1 review
Intervention not reported
0.5% CMC vs 1% CMC · people with dry eye
1 finding from 1 review
Intervention not reported
0.5% CMC vs 0.5% CMC + castor oil vs. 1.0% glycerine + castor oil · people with dry eye
1 finding from 1 review
Intervention not reported
Within ± 0.50 D of target refraction at 12 months post treatment · adult participants (≥ 18 years) with myopia
The intervention showed no clear difference in within ± 0.50 D of target refraction at 12 months post treatment (low certainty).
1 finding from 1 review
RR 0.93 [0.84, 1.03]
Studies not reported
Low
Hot flush frequency (number/day) · women with hot flushes
Oral beta‐estradiol showed no clear difference in frequency of hot flushes Oral beta‐estradiol 0.5‐1.0 mg/day compared with placebo (low certainty).
1 finding from 1 review
Adverse effects Oral beta‐estradiol 0.5‐2.0 mg/day · women with hot flushes
1 finding from 1 review
Dyspnoea ‐ CRQ dyspnoea Scale 1 to 7. Higher is better and 0.5 units is a clinically important difference · patients with chronic obstructive pulmonary disease
1 finding from 1 review
Subgroup: rubella cases Estimated dose 0.2 to 0.5 ml/lb11 Serology +/‐ virus isolation +/‐ clinical signs · susceptible people exposed to rubella
Gamma‐globulin showed no clear difference in subgroup: rubella cases Estimated dose 0.2 to 0.5 ml/lb11 Serology… compared with control (saline or no treatment) (moderate certainty).
1 finding from 1 review
Intervention not reported
Quality of life (dyspnoea) Measured on the CRQ, the output is a number from 0 to 7, where higher on the scale is better. MID is 0.5. · adults with COPD who had exertional dyspnoea but did not fulfil the criteria for long‐term oxygen treatment
The intervention probably leads to higher quality of life (dyspnoea) Measured on the CRQ, the output is a… (moderate certainty).
1 finding from 1 review
Radiographic progression—minimum joint space width (decreased over 0.50 mm during the study period) · patients with osteoarthritis
Diacerein may leads to lower radiographic progression—minimum joint space width (decreased over… compared with placebo (low certainty).
1 finding from 1 review
Antiviral response ‐ 0.5mg/Kg · patients being treated for HIV infection
It is very uncertain whether PRO 140 changes antiviral response: 0.5 mg/kg compared with placebo (very low certainty).
1 finding from 1 review
Individual nadir changes in HIV‐1 RNA level ‐ 0.5mg/Kg · patients being treated for HIV infection
1 finding from 1 review
FEV1 · adults with asthma
1 finding from 1 review
Eyes within ± 0.5 D of target refraction · patients with myopia
Laser‐assisted in‐situ keratomileusis (LASIK) showed no clear difference in within 0.50 D of target refraction compared with photorefractive keratectomy (PRK) (low certainty).
1 finding from 1 review
Pain with dilation ‐ not measured · people requesting a surgical abortion between seven and 14 weeks' gestation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pain with aspirationa,b · people requesting a surgical abortion between seven and 14 weeks' gestation
1 finding from 1 review
Pain during procedure ‐ not measured · people requesting a surgical abortion between seven and 14 weeks' gestation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Clinical improvement (dichotomous) · active EoE pediatric patients
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Clinical improvement (continuous) · active EoE pediatric patients
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Histological improvement (dichotomous) · active EoE pediatric patients
It is very uncertain whether mepolizumab 10 mg/kg changes histological improvement at 12 weeks (dichotomous) compared with mepolizumab 0.55 mg/kg (very low certainty).
1 finding from 1 review