Cochrane · systematic review · CD005135

Laser‐assisted in‐situ keratomileusis (LASIK) versus photorefractive keratectomy (PRK) for myopia

Shortt, AJ, Allan, BDS, Evans, JR · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library

Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 16.7%Very low 1 · 16.7%Low 4 · 66.7%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Laser‐assisted in‐situ keratomileusis (LASIK) versus photorefractive keratectomy (PRK) for myopia

Population: patients with myopia
6 questions
OutcomeEffectEvidenceStatus / GRADE
UCVA of 20/20 or better
Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)
OR 1.64 [1.1, 2.45]7 studies · 1007 participantsLow
Downgraded: risk of bias
Within 0.50 D of target refraction
Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)
OR 1.45 [0.99, 2.1]7 studies · 1007 participantsLow
Downgraded: risk of bias
Postoperative spherical equivalent
Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)
no estimate extracted6 studies · 589 participantsLow
Downgraded: risk of bias
Lost one or more lines of BCVA
Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)
OR 0.88 [0.51, 1.5]6 studies · 746 participantsLow
Downgraded: risk of bias
Final BCVA of 20/40 or less
Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)
OR 0.12 [0.01, 1.93]6 studies · 442 participantsVery low
Downgraded: risk of bias, imprecision
Pain scores
Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)
no estimate extracted0 studies · 3 participantsUngraded