Alpha‐blockers vs placebo
Severity of attacks · primary Raynaud's phenomenon
1 finding from 1 review
- no estimate extracted1 study · 25 participantsGRADE not reported
Findings
What do systematic reviews say?
3,696 questions · 3,815 findings · 855 reviews
No studies found 573 · 15%GRADE not reported 374 · 9.8%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%
Summary of findings table ‐ Intraperitoneal local anaesthetic vs control
Proportion discharged as day surgery · people undergoing laparoscopic cholecystectomy.
It is very uncertain whether summary of findings table ‐ Intraperitoneal local anaesthetic changes proportion discharged as day surgery compared with control (very low certainty).
1 finding from 1 review
- Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for… 2021 · Cochrane Headline outcomes onlyRR 1.43 [0.64, 3.2]3 studies · 242 participantsVery low
Glucocorticoid with cyclophosphamide plus usual care vs placebo or usual care
Mortality at 30 days following the ingestion of paraquat · people with moderate to severe oral paraquat poisoning
The review found no eligible studies for this question.
1 finding from 1 review
- Glucocorticoid with cyclophosphamide for oral paraquat poisoning 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
High levels of PEEP vs low levels of PEEP
Oxygen efficiency (PaO2/FiO2) day 1 postoperative · patients with ALI and ARDS
1 finding from 1 review
- High versus low positive end‐expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute… 2021 · Cochrane Headline outcomes onlyno estimate extracted6 studies · 2594 participantsLow
High levels of PEEP vs low levels of PEEP
Oxygen efficiency (PaO2/FiO2) day 3 postoperative · patients with ALI and ARDS
1 finding from 1 review
- High versus low positive end‐expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute… 2021 · Cochrane Headline outcomes onlyno estimate extracted6 studies · 2309 participantsLow
High levels of PEEP vs low levels of PEEP
Oxygen efficiency (PaO2/FIO2). Day 7 · patients with ALI and ARDS
1 finding from 1 review
- High versus low positive end‐expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute… 2021 · Cochrane Headline outcomes onlyno estimate extracted5 studies · 1611 participantsModerate
High levels of PEEP vs low levels of PEEP
Ventilator‐free days up to day 28 · patients with ALI and ARDS
1 finding from 1 review
- High versus low positive end‐expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute… 2021 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 1654 participantsLow
Schedules involving more vs fewer home visits
Maternal death · mothers and infants receiving home visits in the early postpartum period
It is very uncertain whether schedules involving more changes maternal mortality within 42 days post‐birth compared with fewer home visits (very low certainty).
1 finding from 1 review
- RR 0.39 [0.02, 9.41]1 study · 225 participantsVery low
Schedules involving more vs fewer home visits
Postnatal depression · mothers and infants receiving home visits in the early postpartum period
1 finding from 1 review
- no estimate extracted2 studies · 767 participantsLow
Integrated disease management interventions vs usual care
Hospital days per patient, all causes · patients with chronic obstructive pulmonary disease
1 finding from 1 review
- Integrated disease management interventions for patients with chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes onlyno estimate extracted14 studies · 3563 participantsModerate
Antibiotics vs placebo compared
Relapse · children, aged 2 to 59 months, with WHO‐defined non‐severe pneumonia and wheeze
Antibiotic therapy showed no clear difference in relapse (children who were 'cured' but developed symptoms within… compared with placebo compared to placebo (low certainty).
1 finding from 1 review
- Antibiotic therapy versus no antibiotic therapy for children aged 2 to 59 months with WHO‐defined non‐severe pneumonia… 2021 · Cochrane Headline outcomes onlyRR 1 [0.74, 1.34]3 studies · 2795 participantsLow
Antibiotics vs placebo compared
Adverse effects of antibiotics · children, aged 2 to 59 months, with WHO‐defined non‐severe pneumonia and wheeze
Antibiotic therapy showed no clear difference in treatment harms (adverse events or side effects associated with… compared with placebo compared to placebo (low certainty).
1 finding from 1 review
- Antibiotic therapy versus no antibiotic therapy for children aged 2 to 59 months with WHO‐defined non‐severe pneumonia… 2021 · Cochrane Headline outcomes onlyRR 0.81 [0.6, 1.09]3 studies · 3253 participantsLow
Intervention not reported
Duration of supplemental oxygen (days) · preterm infants less than 30 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome
1 finding from 1 review
- Lung recruitment manoeuvres for reducing mortality and respiratory morbidity in mechanically ventilated neonates 2021 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 44 participantsVery low
Intervention not reported
Duration of ventilatory support (days) · preterm infants less than 30 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome
1 finding from 1 review
- Lung recruitment manoeuvres for reducing mortality and respiratory morbidity in mechanically ventilated neonates 2021 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 44 participantsVery low
Intervention not reported
Duration of continuous positive airway pressure therapy (hours or days) · preterm infants less than 30 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome
The review found no eligible studies for this question.
1 finding from 1 review
- Lung recruitment manoeuvres for reducing mortality and respiratory morbidity in mechanically ventilated neonates 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Intervention not reported
Duration of neonatal intensive care unit stay (hours or days) · preterm infants less than 30 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome
The review found no eligible studies for this question.
1 finding from 1 review
- Lung recruitment manoeuvres for reducing mortality and respiratory morbidity in mechanically ventilated neonates 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Intervention not reported
Duration of hospital stay (days) · preterm infants less than 30 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome
The review found no eligible studies for this question.
1 finding from 1 review
- Lung recruitment manoeuvres for reducing mortality and respiratory morbidity in mechanically ventilated neonates 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Medication reconciliation: pharmacist vs other professionals
Length of stay · adults
1 finding from 1 review
- no estimate extracted6 studies · 3983 participantsLow
Medication reconciliation by pharmacist: database‐assisted MR vs unassisted MR
Length of stay · adults
1 finding from 1 review
- no estimate extracted1 study · 311 participantsLow
Medication reconciliation by trained pharmacist technician vs pharmacist
Length of stay · adults
1 finding from 1 review
- no estimate extracted1 study · 183 participantsLow