Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,908 questions · 3,101 findings · 509 reviews

No studies found 571 · 18.4%GRADE not reported 358 · 11.5%Very low 723 · 23.3%Low 854 · 27.5%Moderate 489 · 15.8%High 106 · 3.4%

Intervention not reported

Hypertension (adverse effect, post‐intervention) · people with Parkinson's disease

The intervention showed no clear difference in hypertension (adverse effect, post‐intervention) (moderate certainty).

1 finding from 1 review

Intervention not reported

Orthostatic hypotension (adverse effect, post‐intervention) · people with Parkinson's disease

The intervention showed no clear difference in orthostatic hypotension (adverse effect, post‐intervention) (moderate certainty).

1 finding from 1 review

Intervention not reported

Hypertension (adverse effect, post‐intervention) · people with Parkinson's disease

The intervention showed no clear difference in hypertension (adverse effect, post‐intervention) (moderate certainty).

1 finding from 1 review

Intervention not reported

Hypertension (adverse effect, post‐intervention) · people with Parkinson's disease

The intervention showed no clear difference in hypertension (adverse effect, post‐intervention) (moderate certainty).

1 finding from 1 review

Intervention not reported

Hypertension (adverse effect, post‐intervention) · people with Parkinson's disease

The intervention showed no clear difference in hypertension (adverse effect, post‐intervention) (moderate certainty).

1 finding from 1 review

Intervention not reported

Orthostatic hypotension (adverse effect, post‐intervention) · people with Parkinson's disease

It is very uncertain whether the intervention changes orthostatic hypotension (adverse effect, post‐intervention) (very low certainty).

1 finding from 1 review

Intervention not reported

Hypertension (adverse effect, post‐intervention) · people with Parkinson's disease

The intervention showed no clear difference in hypertension (adverse effect, post‐intervention) (moderate certainty).

1 finding from 1 review

Treatment route: intravenous corticosteroid vs oral corticosteroid

Treatment failure Need for additional treatment · exacerbations of COPD

Treatment route: intravenous corticosteroid showed no clear difference in treatment failure Need to intensify therapy compared with oral corticosteroid (moderate certainty).

1 finding from 1 review

Behavioural intervention vs control

Smoking cessation at time of surgery ‐ Intensive behavioural intervention (multiple contacts, initiated at least 4 weeks before surgery) · People awaiting surgery

Behavioural intervention probably leads to higher smoking cessation at time of surgery ‐ Intensive behavioural… compared with control (moderate certainty).

1 finding from 1 review

Behavioural intervention vs control

Postoperative morbidity: Any complication ‐ Intensive intervention · People awaiting surgery

Behavioural intervention probably leads to lower postoperative morbidity: Any complication ‐ Intensive intervention compared with control (moderate certainty).

1 finding from 1 review

CERA vs other ESA

Adverse events: hypertension · patients with the anaemia of end‐stage kidney disease undergoing dialysis

CERA showed no clear difference in numbers of adverse events due to hypertension: CERA every 2 weeks… compared with other ESA (high certainty).

1 finding from 1 review

Intervention not reported

Presence of PHN 6 months after the onset of the acute herpetic rash2 Clinical diagnostic criteria for PHN in any intensity · people with acute herpes zoster1
1 finding from 1 review

Intervention not reported

Presence of PHN 4 months after the onset of the acute herpetic rash Clinical diagnostic criteria for PHN in any intensity · people with acute herpes zoster1

The intervention showed no clear difference in presence of PHN 4 months after the onset of the acute herpetic rash… (high certainty).

1 finding from 1 review