Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,550 questions · 1,617 findings · 161 reviews · Neonatal

No studies found 238 · 14.7%GRADE not reported 76 · 4.7%Very low 377 · 23.3%Low 567 · 35.1%Moderate 285 · 17.6%High 74 · 4.6%

Repeated lumbar or ventricular punctures vs conservative treatment

Death or disability · preterm infants less than three months of age with either: a) IVH demonstrated by ultrasound or computed tomography (CT) scan; or b)…

Repeated lumbar or ventricular punctures showed no clear difference in death or disability compared with conservative treatment (high certainty).

1 finding from 1 review

Repeated lumbar or ventricular punctures vs conservative treatment

Death or shunt · preterm infants less than three months of age with either: a) IVH demonstrated by ultrasound or computed tomography (CT) scan; or b)…

Repeated lumbar or ventricular punctures showed no clear difference in death or shunt compared with conservative treatment (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Early amino acids vs Late amino acids

Growth during the first month of life · preterm born neonates
3 findings from 1 review

Summary of findings table ‐ Early amino acids vs Late amino acids

Neurodevelopmental outcomes · preterm born neonates

Summary of findings table ‐ Early amino acids showed no clear difference in neurodevelopmental outcome assessed by any standard tool compared with late amino acids (low certainty).

1 finding from 1 review

Summary of findings table ‐ Transcutaneous bilirubin (TcB) screening vs visual assessment

Readmission for phototherapy for hyperbilirubinemia · newborns for hyperbilirubinemia

Summary of findings table ‐ Transcutaneous bilirubin (TcB) screening probably leads to lower readmission for phototherapy for hyperbilirubinemia compared with visual assessment (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Transcutaneous bilirubin (TcB) screening vs visual assessment

Exchange transfusion · newborns for hyperbilirubinemia

Summary of findings table ‐ Transcutaneous bilirubin (TcB) screening showed no clear difference in exchange transfusion compared with visual assessment (low certainty).

1 finding from 1 review

Summary of findings table ‐ Transcutaneous bilirubin (TcB) screening vs visual assessment

Phototherapy before hospital discharge · newborns for hyperbilirubinemia

Summary of findings table ‐ Transcutaneous bilirubin (TcB) screening probably leads to higher phototherapy before hospital discharge compared with visual assessment (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Transcutaneous bilirubin (TcB) screening vs visual assessment

Acute bilirubin encephalopathy · newborns for hyperbilirubinemia

Summary of findings table ‐ Transcutaneous bilirubin (TcB) screening showed no clear difference in acute bilirubin encephalopathy compared with visual assessment (low certainty).

1 finding from 1 review