Search review questions

Neonatal detection of large‐for‐gestational age · Pregnant women with singleton fetuses who were of 20 weeks' gestation and above.

Perinatal mortality · Pregnant women with singleton fetuses who were of 20 weeks' gestation and above.

Intrauterine death · Pregnant women with singleton fetuses who were of 20 weeks' gestation and above.

Caesarean section · Pregnant women with singleton fetuses who were of 20 weeks' gestation and above.

Neurodevelopmental outcome in childhood · Pregnant women with singleton fetuses who were of 20 weeks' gestation and above.

Admission to neonatal nursery · Pregnant women with singleton fetuses who were of 20 weeks' gestation and above.

Maternal mortality · Pregnant women

Preterm birth · Pregnant women

Perinatal mortality · Pregnant women

Maternal anaemia · Pregnant women

Maternal clinical infection · Pregnant women

Preterm birth · Pregnant women

Maternal mortality · Pregnant women

Perinatal mortality · Pregnant women

Maternal anaemia · Pregnant women

Maternal clinical infection · Pregnant women

Recurrent pyelonephritis · pregnant women with a history of one or more UTI before or during pregnancy

Recurrent UTI (cystitis) · pregnant women with a history of one or more UTI before or during pregnancy

Preterm birth (< 37 weeks) · pregnant women with a history of one or more UTI before or during pregnancy

Birthweight < 2500 (g) · pregnant women with a history of one or more UTI before or during pregnancy

Birthweight (g) · pregnant women with a history of one or more UTI before or during pregnancy

Five‐minute Apgar score < seven · pregnant women with a history of one or more UTI before or during pregnancy

Miscarriages · pregnant women with a history of one or more UTI before or during pregnancy

Perinatal mortality (stillbirth ‐ death of fetus prior to birth; neonatal death ‐ death within the first 28 days of birth; or infant death ‐ death after the first 28 days) · pregnant women with a term suspected compromised baby

Major neonatal morbidity one or more of the following: hypoxic ischaemic encephalopathy (HIE) ‐ grade II or III, necrotising enterocolitis (NEC), need for ongoing ventilation, meconium aspiration syndrome, seizures, need for therapeutic hypothermia · pregnant women with a term suspected compromised baby

Neurodevelopmental disability/impairment CBCL, Ages and Stages Questionnaire · pregnant women with a term suspected compromised baby

Maternal mortality · pregnant women with a term suspected compromised baby

Significant maternal morbidity one or more of the following: significant postpartum haemorrhage requiring blood transfusion; maternal admission to intensive care unit; uterine rupture; hysterectomy · pregnant women with a term suspected compromised baby

Admission to NICU · pregnant women with a term suspected compromised baby

Caesarean section · pregnant women with a term suspected compromised baby

Maternal death · Pregnant women aged 18 to 38 years and an estimated gestation of 20 to 36 weeks.

Infant death (up to 175 days) · Pregnant women aged 18 to 38 years and an estimated gestation of 20 to 36 weeks.

Perinatal death (stillbirth + death in first week of life) · Pregnant women aged 18 to 38 years and an estimated gestation of 20 to 36 weeks.

Any respiratory illness in women · Pregnant women aged 18 to 38 years and an estimated gestation of 20 to 36 weeks.

Any respiratory illness in infants · Pregnant women aged 18 to 38 years and an estimated gestation of 20 to 36 weeks.

Maternal hospitalisation for any infection · Pregnant women aged 18 to 38 years and an estimated gestation of 20 to 36 weeks.

Neonatal hospitalisation due to sepsis within 28 days of birth · Pregnant women aged 18 to 38 years and an estimated gestation of 20 to 36 weeks.

Low birthweight (less than 2500 g) · Women receiving supplements during pregnancy

Side effects (any reported throughout intervention period) · Women receiving supplements in pregnancy

Severe anaemia at any time during second and third trimester (Hb less than 70 g/L) · Women receiving supplements in pregnancy

Maternal clinical malaria or other infection in pregnancy · Women receiving supplements in pregnancy

Birthweight (g) · Women receiving supplements during pregnancy

Premature birth (less than 37 weeks of gestation) · Women receiving supplements during pregnancy

Neonatal death (within 28 days after delivery) · Women receiving supplements during pregnancy

Congenital anomalies (including neural tube defects) · Women receiving supplements during pregnancy

Maternal anaemia at term (Hb less than 110 g/L at 37 weeks' gestation or more) · Women receiving supplements in pregnancy

Maternal iron deficiency at term (based on any indicator of iron status at 37 weeks' gestation or more) · Women receiving supplements in pregnancy

Maternal iron‐deficiency anaemia at term (Hb less than 110 g/L and at least 1 additional laboratory indicators at 37 weeks' gestation or more) · Women receiving supplements in pregnancy

Maternal death (death while pregnant or within 42 days of termination of pregnancy) · Women receiving supplements in pregnancy

Time to resolution of breast abscess (days) · Breastfeeding women with breast abscesses