Cochrane · systematic review · CD009279

Interventions for preventing recurrent urinary tract infection during pregnancy

Schneeberger, C, Geerlings, SE, Middleton, P, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 7 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Nitrofurantoin and close surveillance compared with close surveillance alone for preventing recurrent urinary tract infection during pregnancy

Population: pregnant women with a history of one or more UTI before or during pregnancy
7 questions
OutcomeEffectEvidenceStatus / GRADE
Recurrent pyelonephritis
Nitrofurantoin and close surveillance vs close surveillance alone
RR 0.89 [0.31, 2.53]1 study · 167 participantsVery low
Downgraded: imprecision
Recurrent UTI (cystitis)
Nitrofurantoin and close surveillance vs close surveillance alone
RR 0.3 [0.06, 1.38]1 study · 167 participantsVery low
Downgraded: imprecision
Preterm birth (< 37 weeks)
Nitrofurantoin and close surveillance vs close surveillance alone
RR 1.18 [0.42, 3.35]1 study · 147 participantsVery low
Downgraded: imprecision
Birthweight < 2500 (g)
Nitrofurantoin and close surveillance vs close surveillance alone
RR 2.03 [0.53, 7.8]1 study · 147 participantsVery low
Downgraded: imprecision
Birthweight (g)
Nitrofurantoin and close surveillance vs close surveillance alone
no estimate extracted1 study · 147 participantsVery low
Downgraded: imprecision
Five‐minute Apgar score < seven
Nitrofurantoin and close surveillance vs close surveillance alone
RR 2.03 [0.19, 21.87]1 study · 147 participantsVery low
Downgraded: imprecision
Miscarriages
Nitrofurantoin and close surveillance vs close surveillance alone
RR 3.11 [0.33, 29.29]1 study · 167 participantsVery low
Downgraded: imprecision