What do systematic reviews say?

Rabeprazole at higher doses (1 mg/kg) vs rabeprazole at lower doses (0.5 mg/kg)

• Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 127 participants
  Very low

Rabeprazole at higher doses (1 mg/kg) vs rabeprazole at lower doses (0.5 mg/kg)

• Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 127 participants
  Very low

Rabeprazole at higher doses (1 mg/kg) vs rabeprazole at lower doses (0.5 mg/kg)

• Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 127 participants
  Very low

Rabeprazole at higher doses (1 mg/kg) vs rabeprazole at lower doses (0.5 mg/kg)

The review found no eligible studies for this question.

• Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pantoprazole in higher doses (1.2 mg/kg) vs pantoprazole at lower doses (0.3 mg/kg)

• Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Very low

Pantoprazole in higher doses (1.2 mg/kg) vs pantoprazole at lower doses (0.3 mg/kg)

• Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Very low

Pantoprazole in higher doses (1.2 mg/kg) vs pantoprazole at lower doses (0.3 mg/kg)

The review found no eligible studies for this question.

• Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pantoprazole in higher doses (1.2 mg/kg) vs pantoprazole at lower doses (0.3 mg/kg)

The review found no eligible studies for this question.

• Pharmacological treatment of gastro‐oesophageal reflux in children 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Low‐intensity pulsed ultrasound vs control

• Ultrasound and shockwave therapy for acute fractures in adults 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 393 participants
  Very low

Low‐intensity pulsed ultrasound vs control

The review found no eligible studies for this question.

• Ultrasound and shockwave therapy for acute fractures in adults 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Low‐intensity pulsed ultrasound vs control

• Ultrasound and shockwave therapy for acute fractures in adults 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 370 participants
  Low

Low‐intensity pulsed ultrasound vs control

• Ultrasound and shockwave therapy for acute fractures in adults 2023 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 887 participants
  Very low

Low‐intensity pulsed ultrasound vs control

• Ultrasound and shockwave therapy for acute fractures in adults 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 148 participants
  Very low

Low‐intensity pulsed ultrasound vs control

Low‐intensity pulsed ultrasound showed no clear difference in delayed or non‐union (medium term) compared with control (moderate certainty).

• Ultrasound and shockwave therapy for acute fractures in adults 2023 · Cochrane Headline outcomes only
  RR 1.25 [0.5, 3.09]
  7 studies · 746 participants
  Moderate

Low‐intensity pulsed ultrasound vs control

It is very uncertain whether low‐intensity pulsed ultrasound changes adverse events Reported as skin irritation compared with control (very low certainty).

• Ultrasound and shockwave therapy for acute fractures in adults 2023 · Cochrane Headline outcomes only
  RR 0.94 [0.06, 14.65]
  1 study · 101 participants
  Very low

Summary of findings table ‐ Faster rotation vs slower rotation

• Adapting shift work schedules for sleep quality, sleep duration, and sleepiness in shift workers 2023 · Cochrane Headline outcomes only
  no estimate extracted
  282 participants
  Low

Summary of findings table ‐ Faster rotation vs slower rotation

• Adapting shift work schedules for sleep quality, sleep duration, and sleepiness in shift workers 2023 · Cochrane Headline outcomes only
  no estimate extracted
  282 participants
  Very low

Summary of findings table ‐ Faster rotation vs slower rotation

• Adapting shift work schedules for sleep quality, sleep duration, and sleepiness in shift workers 2023 · Cochrane Headline outcomes only
  no estimate extracted
  62 participants
  Very low

Summary of findings table ‐ Faster rotation vs slower rotation

The review found no eligible studies for this question.

• Adapting shift work schedules for sleep quality, sleep duration, and sleepiness in shift workers 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Higher‐dose vs lower‐dose nicotine patch

Higher‐dose showed no clear difference in smoking cessation ‐ 42/44 mg versus 21/22 mg (24‐hour patches) compared with lower‐dose nicotine patch (moderate certainty).

• Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation 2023 · Cochrane Headline outcomes only
  RR 1.09 [0.93, 1.29]
  5 studies · 1655 participants
  Moderate
• Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation 2023 · Cochrane Headline outcomes only
  RR 1.19 [1, 1.41]
  3 studies · 3446 participants
  Moderate
• Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation 2023 · Cochrane Headline outcomes only
  RR 1.48 [1.06, 2.08]
  1 study · 537 participants
  Moderate