Participants with adverse events ‐ injection site adverse events Clinical criteria · healthy older adults aged ≥ 60 years
Live zoster vaccine probably leads to higher participants with adverse events ‐ injection site adverse… compared with placebo (moderate certainty).
1 finding from 1 review
Dropouts Clinical or laboratory criteria · healthy older adults aged ≥ 60 years
Live zoster vaccine showed no clear difference in dropoutsClinical or laboratory criteria compared with placebo (moderate certainty).
1 finding from 1 review
Participants with adverse events ‐ death Clinical criteria · healthy older adults aged ≥ 60 years
Recombinant zoster vaccine showed no clear difference in participants with adverse events ‐ deathClinical criteria compared with placebo (moderate certainty).
1 finding from 1 review
Iron deficiency (as defined by study authors, based on a biomarker of iron status) · population aged 2 years and above (Andersson 2008 ‐ 5‐18 years, Asibey‐Berko 2007 ~ 3 years, Chen Ke 2008 ‐ 2‐6 years, Haas 2014 ‐ women…
Condiments/seasonings fortified with iron plus other micronutrients may leads to lower iron deficiency (as defined by the trialists based on a biomarker of… compared with condiments/seasonings fortified with other micronutrients except iron (low certainty).
1 finding from 1 review
Ferritin (µg/L) · population aged 2 years and above (Andersson 2008 ‐ 5‐18 years, Asibey‐Berko 2007 ~ 3 years, Chen Ke 2008 ‐ 2‐6 years, Haas 2014 ‐ women…
1 finding from 1 review
Transferrin saturation · population aged 2 years and above (Andersson 2008 ‐ 5‐18 years, Asibey‐Berko 2007 ~ 3 years, Chen Ke 2008 ‐ 2‐6 years, Haas 2014 ‐ women…
1 finding from 1 review
Total iron binding capacity · population aged 2 years and above (Andersson 2008 ‐ 5‐18 years, Asibey‐Berko 2007 ~ 3 years, Chen Ke 2008 ‐ 2‐6 years, Haas 2014 ‐ women…
1 finding from 1 review
Adverse effects · population aged 2 years and above (Andersson 2008 ‐ 5‐18 years, Asibey‐Berko 2007 ~ 3 years, Chen Ke 2008 ‐ 2‐6 years, Haas 2014 ‐ women…
1 finding from 1 review
Haemoglobin (g/dL) · population aged 2 years and above (Ballot 1989a (C) ‐ > 10 years, Chen 2005 (C) ‐ >3 years; Huo 2002 ‐ 11‐17 years, Longfils 2008‐ 6‐21…
1 finding from 1 review
Iron deficiency (as defined by study authors, based on a biomarker of iron status) · population aged 2 years and above (Ballot 1989a (C) ‐ > 10 years, Chen 2005 (C) ‐ >3 years; Huo 2002 ‐ 11‐17 years, Longfils 2008‐ 6‐21…
Condiments/seasonings fortified with iron showed no clear difference in iron deficiency (as defined by the trialists based on a biomarker of… compared with unfortified condiments/seasonings (moderate certainty).
1 finding from 1 review
Ferritin (µg/L) · population aged 2 years and above (Ballot 1989a (C) ‐ > 10 years, Chen 2005 (C) ‐ >3 years; Huo 2002 ‐ 11‐17 years, Longfils 2008‐ 6‐21…
1 finding from 1 review
Transferrin saturation · population aged 2 years and above (Ballot 1989a (C) ‐ > 10 years, Chen 2005 (C) ‐ >3 years; Huo 2002 ‐ 11‐17 years, Longfils 2008‐ 6‐21…
1 finding from 1 review
Total iron binding capacity · population aged 2 years and above (Ballot 1989a (C) ‐ > 10 years, Chen 2005 (C) ‐ >3 years; Huo 2002 ‐ 11‐17 years, Longfils 2008‐ 6‐21…
1 finding from 1 review
Adverse effects · population aged 2 years and above (Ballot 1989a (C) ‐ > 10 years, Chen 2005 (C) ‐ >3 years; Huo 2002 ‐ 11‐17 years, Longfils 2008‐ 6‐21…
1 finding from 1 review
Haemoglobin (g/dL) · population aged 2 years and above (Andersson 2008 ‐ 5‐18 years, Asibey‐Berko 2007 ~ 3 years, Chen Ke 2008 ‐ 2‐6 years, Haas 2014 ‐ women…
1 finding from 1 review
Proportion of participants with one or more serious adverse events · Children and adolescents with ADHD
It is very uncertain whether methylphenidate changes proportion of participants with one or more serious adverse events compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Adverse events considered non‐serious (penicillin versus doxycycline) · Children and adolescents with ADHD
It is very uncertain whether methylphenidate changes proportion of participants with one or more adverse events… compared with placebo or no intervention (very low certainty).
1 finding from 1 review
General behaviour: all parallel‐group trials and first‐period cross‐over trials General behaviour rating scales (Teacher‐rated) · Children and adolescents with ADHD
It is very uncertain whether methylphenidate changes general behaviour: all parallel‐group trials and first‐period… compared with placebo or no intervention (very low certainty).
1 finding from 1 review
QoL · Children and adolescents with ADHD
It is very uncertain whether methylphenidate changes quality of life (parent‐rated) compared with placebo or no intervention (very low certainty).
1 finding from 1 review
50% or greater reduction in seizure frequency · people (aged 12 years and over) with drug‐resistant focal epilepsy
Perampanel add‐on leads to higher ≥ 50% reduction in seizure frequency compared with placebo (high certainty).
1 finding from 1 review