Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,549 questions · 1,604 findings · 181 reviews

No studies found 258 · 16.1%GRADE not reported 69 · 4.3%Very low 337 · 21%Low 406 · 25.3%Moderate 410 · 25.6%High 124 · 7.7%

Summary of findings: intravitreal bevacizumab plus intravitreal steroid vs intravitreal steroid

Raised Intraocular Pressure at · adults with centre‐involving diabetic macular oedema

It is very uncertain whether summary of findings: intravitreal bevacizumab plus intravitreal… changes raised intraocular pressure at 1 year at compared with intravitreal steroid (very low certainty).

1 finding from 1 review

Summary of findings: intravitreal bevacizumab plus intravitreal steroid vs intravitreal anti‐VEGF

Significant intraocular inflammation at · adults with centre‐involving diabetic macular oedema

It is very uncertain whether summary of findings: intravitreal anti‐VEGF plus intravitreal steroid changes significant intraocular inflammation at compared with intravitreal anti‐VEGF (very low certainty).

1 finding from 1 review

Summary of findings: intravitreal bevacizumab plus intravitreal steroid vs intravitreal anti‐VEGF

Development of cataract at · adults with centre‐involving diabetic macular oedema

Summary of findings: intravitreal anti‐VEGF plus intravitreal steroid probably leads to higher development of cataract at compared with intravitreal anti‐VEGF (moderate certainty).

1 finding from 1 review

Summary of findings: intravitreal bevacizumab plus intravitreal steroid vs intravitreal anti‐VEGF

Raised Intraocular Pressure at · adults with centre‐involving diabetic macular oedema

Summary of findings: intravitreal anti‐VEGF plus intravitreal steroid probably leads to higher raised intraocular pressure at compared with intravitreal anti‐VEGF (moderate certainty).

1 finding from 1 review

Summary of findings: intravitreal bevacizumab plus intravitreal steroid vs intravitreal anti‐VEGF

Systemic adverse events at · adults with centre‐involving diabetic macular oedema

Summary of findings: intravitreal anti‐VEGF plus intravitreal steroid showed no clear difference in systemic adverse events at compared with intravitreal anti‐VEGF (low certainty).

1 finding from 1 review

Once‐daily ICS/LABA combined inhalers vs once‐daily LAMA

Mortality (all‐cause) · patients with chronic obstructive pulmonary disease

It is very uncertain whether once‐daily ICS/LABA combined inhalers changes mortality (all‐cause) compared with once‐daily LAMA (very low certainty).

1 finding from 1 review

Once‐daily ICS/LABA combined inhalers vs once‐daily LAMA

Pneumonia · patients with chronic obstructive pulmonary disease

It is very uncertain whether once‐daily ICS/LABA combined inhalers changes pneumonia compared with once‐daily LAMA (very low certainty).

1 finding from 1 review

Once‐daily ICS/LABA combined inhalers vs once‐daily LAMA

Hospital admissions · patients with chronic obstructive pulmonary disease

It is very uncertain whether once‐daily ICS/LABA combined inhalers changes hospital admissions (all‐cause) compared with once‐daily LAMA (very low certainty).

1 finding from 1 review

Intervention not reported

Residual pleural fluid on chest X‐ray at 8 weeks · adults and adolescents with pleural TB

The intervention may leads to lower residual pleural fluid on chest X‐ray at 8 weeks (low certainty).

1 finding from 1 review