Summary of findings: intravitreal bevacizumab plus intravitreal steroid vs intravitreal anti‐VEGF: Significant intraocular inflammation at
It is very uncertain whether summary of findings: intravitreal anti‐VEGF plus intravitreal steroid changes significant intraocular inflammation at compared with intravitreal anti‐VEGF (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of findings: intravitreal anti‐VEGF plus intravitreal steroid vs intravitreal anti‐VEGF Significant intraocular inflammation at · adults with centre‐involving diabetic macular oedema It is very uncertain whether summary of findings: intravitreal anti‐VEGF plus intravitreal steroid changes significant intraocular inflammation at compared with intravitreal anti‐VEGF (very low certainty). Anti‐vascular endothelial growth factor combined with intravitreal steroids for diabetic macular oedema (2018) · Cochrane Headline outcomes only | Peto OR 0.53 [0.05, 5.08] | Not reported | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Anti‐vascular endothelial growth factor combined with intravitreal steroids for diabetic macular oedema 2018 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.