Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,640 questions · 2,709 findings · 446 reviews

No studies found 593 · 21.9%GRADE not reported 241 · 8.9%Very low 538 · 19.9%Low 706 · 26.1%Moderate 516 · 19%High 115 · 4.2%

BRIEF FAMILY INTERVENTION vs usual care

Hospital admissions · patients with schizophrenia

It is very uncertain whether BRIEF FAMILY INTERVENTION changes service utilisation ‐ hospital admission ‐ medium to long term… compared with STANDARD CARE (very low certainty).

1 finding from 1 review

BRIEF FAMILY INTERVENTION vs usual care

Global state: relapse ‐ medium term ‐ not measured · patients with schizophrenia

BRIEF FAMILY INTERVENTION showed no clear difference in global state ‐ relapse ‐ medium to long term relapse rates (clinical… compared with STANDARD CARE (low certainty).

1 finding from 1 review

Glutamine‐supplemented nutrition vs non‐supplemented nutrition

Long‐term mortality (closest to six month) · critically ill patients or receiving major surgery

Glutamine‐supplemented nutrition showed no clear difference in long‐term mortality (closest to six month) compared with non‐supplemented nutrition (moderate certainty).

1 finding from 1 review

Combination of manual therapy, exercise, electrotherapy and oral NSAID vs oral NSAID

Adverse events Pain persisting longer than 2 hours after treatment (during the 3‐week treatment period) · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy, exercise, electrotherapy and oral NSAID may leads to higher adverse events Pain persisting longer than 2 hours after treatment… compared with oral NSAID (low certainty).

1 finding from 1 review

Intervention not reported

Achieved recovery according to predetermined criteria (no longer meeting criteria for depression on K‐SADS or meeting a priori criteria for response on a depression checklist, assessed between 4 and 10 weeks of onset of treatment) · children and adolescents with depression

The intervention showed no clear difference in achieved recovery according to predetermined criteria (no longer… (low certainty).

1 finding from 1 review

Exercise vs control

Symptoms of depression (long‐term) different scales · depression in adults
1 finding from 1 review
  • Exercise for depression 2013 · Cochrane Headline outcomes only
    no estimate extracted
    8 studies · 377 participants
    Low