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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

430 questions in 68 reviews · Tobacco Addiction

current versions
No studies 26 · 6%Ungraded 12 · 2.8%Very low 116 · 27%Low 159 · 37%Moderate 87 · 20.2%High 30 · 7%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Reduction to quit vs no treatment
Smoking cessation (≥ 6 month · people who smoke
Smoking reduction interventions for smoking cessation (2019) · Cochrane
RR 1.74 [0.9, 3.38]6 studies · 1599 participantsVery low
Reduction and pharmacotherapy vs reduction alone
Main analysis (all pharmacotherapy): smoking cessation (≥ 6 month · people who smoke
Smoking reduction interventions for smoking cessation (2019) · Cochrane
RR 1.68 [1.09, 2.58]11 studies · 8636 participantsLow
Reduction and pharmacotherapy vs reduction alone
Subgroup: combination NRT; smoking cessation (≥ 6 month · people who smoke
Smoking reduction interventions for smoking cessation (2019) · Cochrane
RR 1.02 [0.61, 1.69]3 studies · 1124 participantsLow
Reduction and pharmacotherapy vs reduction alone
Subgroup: nicotine patch; smoking cessation (≥ 6 month · people who smoke
Smoking reduction interventions for smoking cessation (2019) · Cochrane
RR 0.34 [0.02, 5.31]1 study · 85 participantsVery low
Reduction and pharmacotherapy vs reduction alone
Subgroup: fast‐acting NRT only; smoking cessation (≥ 6 month · people who smoke
Smoking reduction interventions for smoking cessation (2019) · Cochrane
RR 2.56 [1.93, 3.39]7 studies · 5323 participantsModerate
Reduction and pharmacotherapy vs reduction alone
Subgroup: varenicline only; smoking cessation (≥ 6 month · people who smoke
Smoking reduction interventions for smoking cessation (2019) · Cochrane
RR 3.99 [2.93, 5.44]1 study · 1510 participantsModerate
Reduction and pharmacotherapy vs reduction alone
Subgroup: bupropion only; smoking cessation (≥ 6 month · people who smoke
Smoking reduction interventions for smoking cessation (2019) · Cochrane
RR 1.27 [0.67, 2.4]1 study · 594 participantsLow
Intervention NR
Smoking cessation: performance‐based eligibility competitions versus alternative cessation intervention · tobacco smokers
Competitions for smoking cessation (2019) · Cochrane
no estimate extracted6 studies · 3201 participantsVery low
Intervention NR
Smoking cessation: performance‐based reward competitions versus alternative cessation intervention · tobacco smokers
Competitions for smoking cessation (2019) · Cochrane
no estimate extracted2 studies · 915 participantsVery low
Intervention NR
Smoking cessation at 6+ months · people who smoke cigarettes
Nicotine replacement therapy versus control for smoking cessation (2018) · Cochrane
RR 1.55 [1.49, 1.61]133 studies · 64640 participantsHigh
Intervention NR
Multi‐component, counselling‐based interventions · people who smoke and are involved in the care of young children (birth to 12 years of age)
Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke (2018) · Cochrane
no estimate extracted7 studies · 2880 participantsVery low
Intervention NR
Multi‐component, counselling‐based interventions · people who smoke and are involved in the care of young children (birth to 12 years of age)
Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke (2018) · Cochrane
no estimate extracted3 studies · 8005 participantsVery low
Intervention NR
Multi‐component, education‐based interventions · people who smoke and are involved in the care of young children (birth to 12 years of age)
Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke (2018) · Cochrane
no estimate extracted4 studies · 1401 participantsLow
Intervention NR
In‐person counselling (no additional components) · people who smoke and are involved in the care of young children (birth to 12 years of age)
Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke (2018) · Cochrane
no estimate extracted3 studies · 1483 participantsLow
Intervention NR
Telephone counselling · people who smoke and are involved in the care of young children (birth to 12 years of age)
Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke (2018) · Cochrane
no estimate extracted1 study · 952 participantsLow
Intervention NR
Brief interventions · people who smoke and are involved in the care of young children (birth to 12 years of age)
Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke (2018) · Cochrane
no estimate extracted1 study · 218 participantsVery low
Intervention NR
Multi‐comoponent, education‐based interventions · people who smoke and are involved in the care of young children (birth to 12 years of age)
Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke (2018) · Cochrane
no estimate extracted2 studies · 307 participantsVery low
Intervention NR
In‐person counselling (no additional components) · people who smoke and are involved in the care of young children (birth to 12 years of age)
Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke (2018) · Cochrane
no estimate extracted6 studies · 1001 participantsVery low
Intervention NR
Telephone counselling · people who smoke and are involved in the care of young children (birth to 12 years of age)
Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke (2018) · Cochrane
no estimate extracted1 study · 347 participantsLow
Intervention NR
Multi‐component, counselling‐based interventions · people who smoke and are involved in the care of young children (birth to 12 years of age)
Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke (2018) · Cochrane
no estimate extracted3 studies · 746 participantsVery low
Intervention NR
Multi‐component, education‐based interventions · people who smoke and are involved in the care of young children (birth to 12 years of age)
Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke (2018) · Cochrane
no estimate extracted7 studies · 2936 participantsVery low
Intervention NR
In‐person counselling (no additional components) · people who smoke and are involved in the care of young children (birth to 12 years of age)
Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke (2018) · Cochrane
no estimate extracted8 studies · 1835 participantsVery low
Intervention NR
Telephone counselling · people who smoke and are involved in the care of young children (birth to 12 years of age)
Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke (2018) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Brief interventions · people who smoke and are involved in the care of young children (birth to 12 years of age)
Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke (2018) · Cochrane
no estimate extracted1 study · 100 participantsVery low
Cessation interventions with a partner support component vs cessation interventions without a partner support component
Long‐term smoking abstinence (6 to 9 months) · people who smoked and were willing to be recruited to a cessation programme
Enhancing partner support to improve smoking cessation (2018) · Cochrane
RR 0.97 [0.83, 1.14]13 studies · 2818 participantsLow
Cessation interventions with a partner support component vs cessation interventions without a partner support component
Long‐term smoking abstinence (12 months+) · people who smoked and were willing to be recruited to a cessation programme
Enhancing partner support to improve smoking cessation (2018) · Cochrane
RR 1.04 [0.88, 1.22]7 studies · 2573 participantsLow
Oral and sublingual immunotherapy vs no therapy
Increase in the amount of egg that could be tolerated · children with egg allergy
Oral and sublingual immunotherapy for egg allergy (2018) · Cochrane
RR 7.48 [4.91, 11.38]9 studies · 410 participantsLow
Oral and sublingual immunotherapy vs no therapy
Complete recovery · children with egg allergy
Oral and sublingual immunotherapy for egg allergy (2018) · Cochrane
RR 4.25 [2.77, 6.53]10 studies · 439 participantsLow
Oral and sublingual immunotherapy vs no therapy
Numbers of children with serious adverse events · children with egg allergy
Oral and sublingual immunotherapy for egg allergy (2018) · Cochrane
no estimate extracted10 studies · 439 participantsLow
Oral and sublingual immunotherapy vs no therapy
Number of children with mild‐to‐severe adverse events · children with egg allergy
Oral and sublingual immunotherapy for egg allergy (2018) · Cochrane
RR 8.35 [5.31, 13.12]10 studies · 439 participantsLow
Intervention NR
Smoking rates ( · Young people aged less than 25 years
Mass media interventions for preventing smoking in young people (2017) · Cochrane
no estimate extracted8 studies · 90125 participantsVery low
Group‐format behavioural programmes vs alternative support
Outcome: Smoking cessation assessed at least 6 months after start of treatment, based on self‐report, ± biochemical validation of abstinence · People who smoke
Group behaviour therapy programmes for smoking cessation (2017) · Cochrane
no estimate extractedNRNo studies
Group‐format behavioural programmes vs alternative support
Group programme compared to self‐help programme · People who smoke
Group behaviour therapy programmes for smoking cessation (2017) · Cochrane
RR 1.88 [1.52, 2.33]13 studies · 4395 participantsModerate
Group‐format behavioural programmes vs alternative support
Group programme compared to brief support · People who smoke
Group behaviour therapy programmes for smoking cessation (2017) · Cochrane
RR 1.25 [1.07, 1.46]16 studies · 7601 participantsLow
Group‐format behavioural programmes vs alternative support
Group programme compared to face‐to‐face individual intervention · People who smoke
Group behaviour therapy programmes for smoking cessation (2017) · Cochrane
RR 0.99 [0.76, 1.28]6 studies · 980 participantsModerate
Group‐format behavioural programmes vs alternative support
Group programme plus pharmacotherapy versus pharmacotherapy and brief support alone · People who smoke
Group behaviour therapy programmes for smoking cessation (2017) · Cochrane
RR 1.11 [0.93, 1.33]5 studies · 1523 participantsModerate
Group‐format behavioural programmes vs alternative support
Group programme versus 'no intervention' controls · People who smoke
Group behaviour therapy programmes for smoking cessation (2017) · Cochrane
RR 2.6 [1.8, 3.76]9 studies · 1098 participantsLow
Intervention NR
Smoking cessation at longest · Adult smokers
Nursing interventions for smoking cessation (2017) · Cochrane
RR 1.29 [1.21, 1.38]44 studies · 20881 participantsModerate
Intervention NR
Smoking cessation at longest · Adult smokers
Nursing interventions for smoking cessation (2017) · Cochrane
RR 1.29 [1.21, 1.38]37 studies · 16865 participantsModerate
Intervention NR
Smoking cessation at longest · Adult smokers
Nursing interventions for smoking cessation (2017) · Cochrane
RR 1.27 [0.99, 1.62]7 studies · 4016 participantsModerate
Individual counselling vs minimal contact control
Smoking cessation at longest · People who smoke
Individual behavioural counselling for smoking cessation (2017) · Cochrane
RR 1.57 [1.4, 1.77]27 studies · 11100 participantsHigh
Individual counselling vs minimal contact control
Smoking cessation at longest · People who smoke
Individual behavioural counselling for smoking cessation (2017) · Cochrane
RR 1.24 [1.01, 1.51]6 studies · 2662 participantsModerate
More intensive vs less intensive counselling
Smoking cessation at longest · People who smoke
Individual behavioural counselling for smoking cessation (2017) · Cochrane
RR 1.29 [1.09, 1.53]11 studies · 2920 participantsHigh
Behavioural interventions vs minimal control
Comparisons and outcomes1 · young people
Tobacco cessation interventions for young people (2017) · Cochrane
no estimate extractedNRNo studies
Pharmacological interventions vs placebo
Bupropion vs placebo Smoking cessation · young people
Tobacco cessation interventions for young people (2017) · Cochrane
RR 1.49 [0.55, 4.02]1 study · 207 participantsVery low
Pharmacological interventions vs placebo
Bupropion vs placebo Adverse events · young people
Tobacco cessation interventions for young people (2017) · Cochrane
no estimate extracted1 study · 207 participantsVery low
Pharmacological interventions vs placebo
Nicotine patch + bupropion vs nicotine patch + placebo Smoking cessation · young people
Tobacco cessation interventions for young people (2017) · Cochrane
RR 1.05 [0.41, 2.69]1 study · 211 participantsVery low
Pharmacological interventions vs placebo
Nicotine patch + bupropion vs nicotine patch + placebo Adverse events · young people
Tobacco cessation interventions for young people (2017) · Cochrane
no estimate extracted1 study · 211 participantsVery low
Behavioural interventions vs minimal control
Individual counselling (in‐person) vs control Smoking cessation · young people
Tobacco cessation interventions for young people (2017) · Cochrane
RR 1.07 [0.83, 1.39]7 studies · 2088 participantsLow
Behavioural interventions vs minimal control
Group counselling vs control Smoking cessation · young people
Tobacco cessation interventions for young people (2017) · Cochrane
RR 1.35 [1.03, 1.77]9 studies · 1910 participantsLow