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Evidence found and GRADE certainty

897 questions · 966 findings · 73 reviews

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No studies found 269 · 27.8%GRADE not reported 101 · 10.5%Very low 284 · 29.4%Low 180 · 18.6%Moderate 107 · 11.1%High 25 · 2.6%

Medical or surgical intervention, or both, for gastro‐oesophageal reflux disease vs nil intervention, delayed intervention control, or placebo

Exacerbations: number of people experiencing moderate or severe exacerbations · treatment for asthma in adults and children with asthma and GORD

Medical or surgical intervention, or both, for gastro‐oesophageal… showed no clear difference in number of participants with moderate/severe acute exacerbations… compared with nil intervention, delayed intervention control, or placebo (low certainty).

1 finding from 1 review

Medical or surgical intervention, or both, for gastro‐oesophageal reflux disease vs nil intervention, delayed intervention control, or placebo

Lung function: FEV1 mL (change from baseline) · treatment for asthma in adults and children with asthma and GORD
1 finding from 1 review

Medical or surgical intervention, or both, for gastro‐oesophageal reflux disease vs nil intervention, delayed intervention control, or placebo

Use of "rescue" medications and emergency action plans: B2 use puffs per day Duration of treatment: range 14 weeks to 24 weeks · treatment for asthma in adults and children with asthma and GORD
1 finding from 1 review

Topical NSAID (ketoprofen lysinate mouthwash, 160 mg) vs Topical NSAID (benzidamine hydrochloride mouthwash, 22.5 mg)

Failure to complete orthodontic treatment due to pain · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

The review found no eligible studies for this question.

1 finding from 1 review

Any Psychosocial plus any Pharmacological vs any Pharmachological alone compared to

Dropout · patients with opioid detoxification

Any Psychosocial plus any Pharmacological probably leads to lower dropouts ‐ All studies objective compared with any Pharmachological alone compared to (moderate certainty).

1 finding from 1 review

Any Psychosocial plus any Pharmacological vs any Pharmachological alone compared to

Dropout ‐ Studies with low risk of bias · patients with opioid detoxification

Any Psychosocial plus any Pharmacological leads to lower dropouts ‐ Only studies with low risk of bias objeive compared with any Pharmachological alone compared to (high certainty).

1 finding from 1 review

Any Psychosocial plus any Pharmacological vs any Pharmachological alone compared to

Results at · patients with opioid detoxification

Any Psychosocial plus any Pharmacological probably leads to lower results at compared with any Pharmachological alone compared to (moderate certainty).

2 findings from 1 review

Any Psychosocial plus any Pharmacological vs any Pharmachological alone compared to

Compliance as clinical absences during the tratment objective · patients with opioid detoxification

Any Psychosocial plus any Pharmacological probably leads to lower compliance as clinical absences during the tratment objective compared with any Pharmachological alone compared to (moderate certainty).

1 finding from 1 review

Oral anti‐diabetic pharmacological therapies vs placebo (outcomes

Hypertensive disorders of pregnancy · women diagnosed with gestational diabetes; 24‐30 weeks' gestation; singleton pregnancy.

It is very uncertain whether oral anti‐diabetic pharmacological therapies changes hypertensive disorders of pregnancy ‐ (any type) compared with placebo ‐ maternal outcomes (very low certainty).

1 finding from 1 review