Cochrane · systematic review · CD005031

Psychosocial and pharmacological treatments versus pharmacological treatments for opioid detoxification

Amato, L, Minozzi, S, Davoli, M, et al. · Cochrane Database of Systematic Reviews · 2011 · Cochrane Library

Drugs and Alcohol3 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 4 · 66.7%High 2 · 33.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

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Any Psychosocial plus any Pharmacological versus any Pharmachological alone compared to for opioid detoxification

Population: patients with opioid detoxification
6 questions
OutcomeEffectEvidenceStatus / GRADE
Dropouts ‐ All studies objective
Any Psychosocial plus any Pharmacological vs any Pharmachological alone compared to
RR 0.71 [0.59, 0.85]6 studies · 424 participantsModerate
Downgraded: risk of bias
Dropouts ‐ Only studies with low risk of bias objeive
Any Psychosocial plus any Pharmacological vs any Pharmachological alone compared to
RR 0.72 [0.58, 0.88]5 studies · 373 participantsHigh
Use of opiate during the treatment objective
Any Psychosocial plus any Pharmacological vs any Pharmachological alone compared to
RR 0.82 [0.71, 0.93]4 studies · 320 participantsModerate
Downgraded: risk of bias
Results at
Any Psychosocial plus any Pharmacological vs any Pharmachological alone compared to
RR 0.66 [0.53, 0.82]3 studies · 208 participantsModerate
Downgraded: risk of bias
Results at
Any Psychosocial plus any Pharmacological vs any Pharmachological alone compared to
RR 0.84 [0.68, 1.04]2 studies · 89 participantsHigh
Compliance as clinical absences during the tratment objective
Any Psychosocial plus any Pharmacological vs any Pharmachological alone compared to
RR 0.48 [0.38, 0.59]3 studies · 1138 participantsModerate
Downgraded: risk of bias