Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
Intralesional steroid injection plus adjunctive treatment showed no clear difference in maximal mouth opening (interincisal distance) compared with intralesional steroid injection alone (low certainty).
2 findings from 1 review
Adverse effects of therapy · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
1 finding from 1 review
Any adverse effect related to aPDT · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
1 finding from 1 review
Risk with control: 23 studies reported that no adverse effects of aPDT were observed. Number of participants (studies): 639 (24 studies). Certainty: Moderate. (24 studies reported adverse effects, with all studies…
24 studies · 639 participants
Moderate
Subjective evaluation (SAQ General) – PSSE plus bracing vs bracing alone · adolescents with idiopathic scoliosis
1 finding from 1 review
Effect on later sexual function · symptomatic or early postmenopausal women1.
1 finding from 1 review
5c. Moderate‐to‐severe neurodevelopmental disability or intellectual impairment after 2 years of age – doxapram as an adjunct to methylxanthine compared to methylxanthine alone for the treatment of apnea · treatment of apnea
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
side‐effects ‐ side‐effects causing abandon · treatment of apnea
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
5c. Moderate‐to‐severe neurodevelopmental disability or intellectual impairment after 2 years of age – doxapram as an adjunct to methylxanthine compared to methylxanthine alone for the prevention of reintubation · prevention of reintubation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
side‐effects ‐ side‐effects causing abandon · prevention of reintubation
It is very uncertain whether doxapram changes 6c. Side effects causing cessation of therapy – doxapram as an… compared with no treatment, placebo, methylxanthine (including theophylline,… (very low certainty).
1 finding from 1 review
Malaria infection incidence alone( · people living in malaria‐endemic areas
Topical repellents showed no clear difference in malaria infection incidence alone( compared with placebo or no treatment (low certainty).
1 finding from 1 review
Locoregional control · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Concomitant (concurrent) chemoradiotherapy led to lower locoregional control, concurrent chemoradiotherapy (platinum +… compared with radiotherapy alone (non-resectable tumours); GRADE not reported.
1 finding from 1 review
RR 0.75 [0.61, 0.93]
3 studies
GRADE not reported
Disease-free survival · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Concomitant (concurrent) chemoradiotherapy led to lower disease-free survival, concurrent chemoradiotherapy vs radiotherapy… compared with radiotherapy alone (non-resectable tumours); GRADE not reported.
1 finding from 1 review
HR 0.74 [0.67, 0.80]
13 studies
GRADE not reported
Overall survival, adjuvant concomitant chemoradiotherapy vs post-surgery radiotherapy alone · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Concomitant (concurrent) chemoradiotherapy probably leads to lower overall survival, concurrent chemoradiotherapy vs radiotherapy alone… compared with radiotherapy alone (non-resectable tumours) (moderate certainty).
1 finding from 1 review
Adverse effects: drowsiness (gabapentin alone) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether anticonvulsants (gabapentin 300 mg/day) changes adverse effects: drowsiness (gabapentin alone) compared with placebo (very low certainty).
1 finding from 1 review
Intervention not reported
Number of patients with arrhythmia: Garlicin injection plus supportive therapy versus supportive therapy alone · patients with viral myocarditis
It is very uncertain whether the intervention changes number of patients with arrhythmia: Garlicin injection plus… (very low certainty).
1 finding from 1 review
Intervention not reported
Number of patients with arrhythmia: Danhong injection plus supportive therapy versus supportive therapy alone · patients with viral myocarditis
The intervention showed no clear difference in number of patients with arrhythmia: Danhong injection plus… (moderate certainty).
1 finding from 1 review
Intervention not reported
Number of patients with premature beat: Shortscape Fleabane injection plus supportive therapy versus supportive therapy alone · patients with viral myocarditis
The intervention showed no clear difference in number of patients with premature beat: Shortscape Fleabane… (low certainty).
1 finding from 1 review
Intervention not reported
Number of patients with premature beat: Astragaloside injection plus supportive therapy versus supportive therapy alone · patients with viral myocarditis
The intervention showed no clear difference in number of patients with premature beat: Astragaloside injection plus… (low certainty).
1 finding from 1 review
Intervention not reported
Number of patients with premature beat: Danhong injection plus supportive therapy versus supportive therapy alone · patients with viral myocarditis
The intervention probably leads to lower number of patients with premature beat: Danhong injection plus… (moderate certainty).
1 finding from 1 review
Intervention not reported
Number of patients with arrhythmia: Astragaloside injection plus supportive therapy versus supportive therapy alone · patients with viral myocarditis
It is very uncertain whether the intervention changes number of patients with arrhythmia: Astragaloside injection plus… (very low certainty).
1 finding from 1 review