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Evidence found and GRADE certainty

1,490 questions · 1,526 findings · 124 reviews

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No studies found 263 · 17.2%GRADE not reported 224 · 14.7%Very low 292 · 19.1%Low 327 · 21.4%Moderate 286 · 18.7%High 134 · 8.8%

Mammography in combination with breast ultrasonography vs mammography alone

Biopsy rate in women with dense breasts · breast cancer screening in women at average risk with dense breasts

Mammography in combination with breast ultrasonography leads to higher biopsy rate in women with dense breasts compared with mammography alone (high certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Incremental cancer detection for women with non‐dense breasts: cohort studies · breast cancer screening (non‐dense breasts)

Mammography in combination with breast ultrasonography probably leads to higher incremental cancer detection for women with non‐dense breasts: RCT compared with mammography alone (moderate certainty).

2 findings from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Interval cancer · breast cancer screening (non‐dense breasts)

Mammography in combination with breast ultrasonography showed no clear difference in interval cancer compared with mammography alone (high certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

False‐positive rate in women with non‐dense breasts · breast cancer screening (non‐dense breasts)

Mammography in combination with breast ultrasonography leads to higher false‐positive rate in women with non‐dense breasts compared with mammography alone (high certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

False‐negative rate in women with non‐dense breasts · breast cancer screening (non‐dense breasts)

Mammography in combination with breast ultrasonography probably leads to lower false‐negative rate in women with non‐dense breasts compared with mammography alone (moderate certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Biopsy rate in women with non‐dense breasts · breast cancer screening (non‐dense breasts)

Mammography in combination with breast ultrasonography leads to higher biopsy rate in women with non‐dense breasts compared with mammography alone (high certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Incremental cancer detection: cohort studies · s of women with dense and non‐dense breasts

Mammography in combination with breast ultrasonography leads to higher incremental cancer detection: RCT compared with mammography alone (high certainty).

2 findings from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Incremental detection of invasive cancers · s of women with dense and non‐dense breasts

Mammography in combination with breast ultrasonography showed no clear difference in incremental detection of invasive cancers: RCT compared with mammography alone (low certainty).

2 findings from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Interval cancer · s of women with dense and non‐dense breasts

Mammography in combination with breast ultrasonography leads to lower interval cancer compared with mammography alone (high certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Lymph node status · s of women with dense and non‐dense breasts

Mammography in combination with breast ultrasonography probably leads to lower lymph node status compared with mammography alone (moderate certainty).

1 finding from 1 review

Cervical cerclage in combination with antibiotics and tocolytics vs cervical cerclage

Serious neonatal morbidity

It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes serious neonatal morbidity (Reported in Miller 2014 as 'composite… compared with cervical cerclage alone (very low certainty).

1 finding from 1 review

Cervical cerclage in combination with antibiotics and tocolytics vs cervical cerclage

Perinatal loss: all ‐ including miscarriages and stillbirth (Note: data not available for neonatal death)

It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes perinatal loss: all ‐ including miscarriages and stillbirth (Note:… compared with cervical cerclage alone (very low certainty).

1 finding from 1 review